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SCN10A: sodium voltage-gated channel alpha subunit 10
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Gene · 6336

Papers2,467

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

1 to 20 of 2,467

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TitleJournalYearPMIDFound bySource
Suzetrigine: A Selective Inhibitor of the NaV1.8 Sodium Channel.Cureus202642807747PubTator, text miningPubMed
Chasing the Wrong Door for 30 Years: Is Suzetrigine the Key to Selective Pain Relief?Medicina (Kaunas)202642796305PubTator, text miningPubMed
Suzetrigine for Postoperative Pain in Head and Neck Free Flap or Transoral Robotic Surgery.JAMA Otolaryngol Head Neck Surg202642752794PubTator, text miningPubMed
Deeper delving Nav1.8 inhibitor Suzetrigine in chronic pain.Acta Pharmacol Sin202642745014PubTator, text miningPubMed
First-in-Human Phase I Trial of HRS-2129, a Selective Nav1.8 Inhibitor: Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics in Healthy Subjects.Drug Des Devel Ther202642712963PubTator, text miningPubMed
Myotonic Muscle Activity Drives a Persistent Pain State Responsive to NaV1.8-directed Analgesics.J Clin Invest202642709487PubTator, text miningPubMed
A designer saxitoxin-engineered sodium channel pair as a general tool for subtype-selective inhibition.Cell Chem Biol202642679814PubTator, text miningPubMed
Human α1-Antitrypsin Inhibits Nociceptor Excitability and Relieves Inflammatory and Neuropathic Pain.Biomolecules202642650742PubTator, text miningPubMed
Suzetrigine (Journavx) for Acute Dental Pain: First Clinical Case Series of a Selective Naᵥ1.8 Inhibitor in Endodontics.J Endod202642641947PubTator, text miningPubMed
Safinamide dual molecular mechanisms: sodium channel and glutamate modulation as a translational rationale for neuropathic pain - A narrative review.Drug Metab Pers Ther202642639659PubTator, text miningPubMed
Discovery and characterization of pyridazino[4,5-b]indol-4-one derivatives as NaV1.8 inhibitors: A novel approach for targeting chronic pain.Bioorg Chem202642628380PubTator, text miningPubMed
Obesity-driven low-grade chronic inflammation as a mechanistic bridge to chronic pain: from adipose tissue remodeling to central sensitization.Front Immunol202642597587PubTator, text miningPubMed
Nonaddictive Analgesia: New Approaches That Target the Hodgkin-Huxley NaV/KV Dyad.Annu Rev Pharmacol Toxicol202642594287PubTator, text miningPubMed
From ion channel biology to clinical practice: suzetrigine as a precision analgesic.Front Med (Lausanne)202642591799PubTator, text miningPubMed
Short Cationic ACTH-Related Peptides Can Modulate the NaV1.8 Channel Functioning, Resulting in an Analgesic Effect.Int J Mol Sci202642589448PubTator, text miningPubMed
Hydroxyethyl starch surface-modified semi-solid lipid microparticles for sustained intramuscular delivery of progesterone with improved local tolerability.Carbohydr Polym202642586703PubTator, text miningPubMed
Functional characterization of human iPSC-derived sensory neuron processes in microfluidic cultures.Stem Cells Transl Med202642571974PubTator, text miningPubMed
Suzetrigine as Part of Multimodal Therapy Enables Opioid-Free Recovery after Laparoscopic or Arthroscopic Procedures.Pain Ther202642570176PubTator, text miningPubMed
Targeting the peripheral nervous system in adipose tissue with engineered AAV vectors.Cell Rep Methods202642537649PubTator, text miningPubMed
Exploring GC-MS-Based Phytochemistry and Network Pharmacology to Elucidate the Multi-Target Therapeutic Potential of Betel Leaf Oil as an Analgesic and Anti-Inflammatory Agent.Biomed Chromatogr202642530450PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

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Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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