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CCL2: C-C motif chemokine ligand 2

1 protein, 326 patents, 1 drug, 2 trials, 27,312 NIH grants and 83,902 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolCCL2HGNC
NameC-C motif chemokine ligand 2HGNC
NCBI Gene ID6347NCBI Gene
HGNC IDHGNC:10618HGNC
EnsemblENSG00000108691NCBI Gene
AliasesGDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, MGC9434, SCYA2, SMC-CFNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P13500C-C motif chemokine 29914Ensembl, GeneID, HGNCUniProt

Patents 326

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4750797 A12026-06-0345P13500Espacenet
JP 2026067320 A2026-04-201P13500Espacenet
EP 4705273 A22026-03-11337P13500Espacenet
JP 2025538460 A2025-11-289P13500Espacenet
EP 4650780 A22025-11-19645P13500Espacenet
KR 1020250152054 A2025-10-229P13500Espacenet
JP 2025147176 A2025-10-062138P13500Espacenet
JP 2025147176 A2025-10-0616630P13500Espacenet
EP 4619012 A12025-09-249P13500Espacenet
EP 4619419 A22025-09-2435P13500Espacenet

Drugs 1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
CARLUMABCHEMBL1742999C-C motif chemokine 2 inhibitorINHIBITORChEMBL

Trials 2

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT00992186CARLUMABPHASE22013-05-20ClinicalTrials.gov
NCT00786201CARLUMABPHASE2ClinicalTrials.gov

NIH grants 27312

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant1492,025NIH's project files
P30CA008748Cancer Center Support Grant1272,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award1132,025NIH's project files
P30MH062512HIV Neurobehavioral Research Center902,025NIH's project files
P51OD011104Tulane National Primate Research Center832,025NIH's project files
P30DK020572Michigan Diabetes Research Center (MDRC)562,025NIH's project files
P30DK040561Boston Area Nutrition Obesity Research Center (NORC)532,025NIH's project files
P30CA047904Cancer Center Support Grant522,025NIH's project files
P30CA016058Cancer Center Support Grant492,025NIH's project files
ZIAHD002400The Role Of Subclinical Infection And Cytokines In Preterm Parturition482,025NIH's project files

Papers 83902

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42825912PubTator, text miningPubMed
42823263PubTator, text miningPubMed
42820599PubTator, text miningPubMed
42819570PubTator, text miningPubMed
42817189PubTator, text miningPubMed
42816701PubTator, text miningPubMed
42815594PubTator, text miningPubMed
42814578PubTator, text miningPubMed
42813024PubTator, text miningPubMed
42812766PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license