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Gene · 6375

XCL1: X-C motif chemokine ligand 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. XCL1: X-C motif chemokine ligand 1. Genes, record 6375. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6375

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Gene

Symbol
XCL1
HGNC
Name
X-C motif chemokine ligand 1
HGNC
NCBI Gene ID
6375
NCBI Gene
HGNC ID
HGNC:10645
HGNC
Ensembl
ENSG00000143184
NCBI Gene
Aliases
ATAC, LPTN, LTN, SCM-1, SCM-1a, SCM1, SCM1A, SCYC1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P47992Lymphotactin1147Ensembl, GeneID, HGNC

Source UniProt

Patents151

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026120675 A2026-07-22762P47992Espacenet
EP 4705273 A22026-03-11247P47992Espacenet
JP 2026004568 A2026-01-1440989P47992Espacenet
WO 2025260013 A12025-12-188P47992Espacenet
EP 4650780 A22025-11-198304P47992Espacenet
EP 4641203 A22025-10-29240P47992Espacenet
JP 2025147176 A2025-10-0614356P47992Espacenet
JP 2025147176 A2025-10-0616794P47992Espacenet
JP 2025529142 A2025-09-048097P47992Espacenet
EP 4608443 A12025-09-0310P47992Espacenet

1 to 10 of 151

See all 151 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,721

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleXCL1 papersNewest fiscal year
ZIALM202011Predictions and experimental validation of fold-switching proteins102025
P30CA016672Cancer Center Support Grant92025
P30CA008748Cancer Center Support Grant82025
R37AI058072Structural Basis for Chemokine Function82025
P30AI027763UCSF-Bay Area Center for AIDS Research52025
P30CA014051Cancer Center Support (Core) Grant52025
P30CA068485Cancer Center Support Grant52025
P30CA196521The Tisch Cancer Institute - Cancer Center Support Grant52025
U19AI118626Respiratory pathogen-specific T cell signatures following vaccination, natural infection, and treatment52025
U19AI128949Human anti-viral immune responses in tissues and circulation52025

1 to 10 of 1,721Source NIH's project files

See all 1,721 nih grants

Papers2,385

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Thermodynamics and Kinetics of Dimerization-Coupled Fold Switching in the Chemokine XCL1.Proteins202642802474PubTator, text miningPubMed
Genetic Regulation of DNA Methylation and Its Mediating Role in Blood Pressure: A Genome-Wide Twin Study.MedComm (2020)202642756691PubTator, text miningPubMed
Assay for Transposase-Accessible Chromatin Sequencing (ATAC-seq) of Cancer Cells in Culture.Methods Mol Biol202642642593PubTator, text miningPubMed
Step-brothers in arms, SAGA and ATAC co-activator complexes, use different strategies.EMBO J202642581098PubTator, text miningPubMed
SBRT embedded in low-dose RT plus αPD-1 (immuno-EclipseRT, iERT) elicits CD8+ T cell immunity against bulky tumors via an IFN-I/NK/DC axis.Nat Commun202642420294PubTator, text miningPubMed
Long non-coding RNA CARDINAL cis-activates MYOCD expression by recruiting histone reader ZZZ3 in vascular smooth muscle cell phenotype alteration.Cardiovasc Res202642417424PubTator, text miningPubMed
Neutrophil extracellular traps drive local tumor progression and metastasis following thermal ablation in liver cancer via TLR9-mediated inflammatory feedback and immunosuppression.J Immunother Cancer202642413984PubTator, text miningPubMed
PD-L1-targeted OMV priming licenses myeloid co-stimulation and chemokine circuits to potentiate CAR-T therapy in advanced-stage solid tumors.J Nanobiotechnology202642337606PubTator, text miningPubMed
Multi-layered functional genomics prioritizes candidate effectors and regulatory mechanisms of ankylosing spondylitis.Front Immunol202642305533PubTator, text miningPubMed
A ubiquitinated E2-based mRNA vaccine confers complete protection against lethal challenge with classical swine fever virus.J Virol202642283466PubTator, text miningPubMed

1 to 10 of 2,385

See all 2,385 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/6375

GET https://conductscience.org/api/genes/v1/6375/patents?page=2