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Gene · 6386

SDCBP: syndecan binding protein

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. SDCBP: syndecan binding protein. Genes, record 6386. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6386

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Gene

Symbol
SDCBP
HGNC
Name
syndecan binding protein
HGNC
NCBI Gene ID
6386
NCBI Gene
HGNC ID
HGNC:10662
HGNC
Ensembl
ENSG00000137575
NCBI Gene
Aliases
MDA-9, MDA9, SDCBP1, ST1, SYCL, TACIP18
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O00560Syntenin-129865Ensembl, GeneID, HGNC

Source UniProt

Patents32

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-191784O00560Espacenet
JP 2025517970 A2025-06-121784O00560Espacenet
JP 2024009871 A2024-01-23104O00560Espacenet
US 11446398 B22022-09-2085833O00560Espacenet
US 11446398 B22022-09-2085837O00560Espacenet
JP 2022537339 A2022-08-2516O00560Espacenet
US 11400116 B22022-08-02501O00560Espacenet
US 11400116 B22022-08-023328O00560Espacenet
JP 2022524081 A2022-04-27188804O00560Espacenet
JP 2022524081 A2022-04-27188808O00560Espacenet

1 to 10 of 32

See all 32 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,458

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleSDCBP papersNewest fiscal year
P30CA016059Massey Cancer Center - Cancer Center Support Grant142025
R35CA197570Early to Late Events in Colorectal Neoplasia: Basic Biology to Clinical Implementation82025
P30CA068485Cancer Center Support Grant62025
P30DK058404Molecular and Cellular Basis for Digestive Diseases62025
R35HL150807Functional role and therapeutic targeting of exosomes and extracellular RNA biomarkers in heart failure62025
P30CA016672Cancer Center Support Grant52025
R01NS125016Engineering Extracellular Vesicles of Human Brain Organoids for Stroke Therapy52025
P20GM130423The Kansas Institute for Precision Medicine42025
P30EY005722Center Core Grant for Vision Research42025
K12GM093857Virginia Commonwealth University IRACDA32025

1 to 10 of 1,458Source NIH's project files

See all 1,458 nih grants

Papers2,794

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
SDCBP competes with CBL to stabilize PES1 and promote c-Myc translation in ESCC tumorigenesis.Cell Rep202642771522PubTator, text miningPubMed
Tumor-derived KLK5 activates TMEM158+ cancer-associated fibroblasts to induce CD8+ T cell exhaustion and confer immunotherapy resistance in lung cancer.Drug Resist Updat202642759446PubTator, text miningPubMed
A guide to selecting high-performing antibodies for Syntenin-1 (O00560) for use in western blot, immunoprecipitation, and immunofluorescence.F1000Res202642732170PubTator, text miningPubMed
Molecular Detection and Subtype Characterization of Blastocystis spp. in Symptomatic Children Using PCR and Sequencing.Iran J Parasitol202642598108PubTator, text miningPubMed
Inhibitory TIGIT signaling is dependent on T cell receptor activation.Cell Rep202642560817PubTator, text miningPubMed
SDCBP Cooperates With YBX1 to Promote ESCC Metastasis by Forming a Positive Feedback Loop With Wnt-β-Catenin Signaling Pathway.J Biochem Mol Toxicol202642517420PubTator, text miningPubMed
Enhanced Discrimination of Coronary Artery Disease Severity by Circulating Phoenixin-14: Evidence from a Clinical Laboratory Study.Int J Mol Sci202642449992PubTator, text miningPubMed
Extracellular vesicle cargo dynamics in the bone marrow microenvironment: from hematopoietic homeostasis to malignant transformation.Extracell Vesicle202642344609PubTator, text miningPubMed
Targeting MDA-9/syntenin-1 (SDCBP) as a strategy to eliminate head and neck squamous cell carcinoma stem cells.Cancer Lett202642342022PubTator, text miningPubMed
Small extracellular vesicle-mediated transfer of HPV16 transcripts from Ca Ski cells increases proliferation of HPV-negative recipient cancer cells.Cell Commun Signal202642298561PubTator, text miningPubMed

1 to 10 of 2,794

See all 2,794 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/6386

GET https://conductscience.org/api/genes/v1/6386/patents?page=2