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SDHA: succinate dehydrogenase complex flavoprotein subunit A

1 protein, 73 patents, 0 drugs, 0 trials, 2,521 NIH grants and 4,997 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolSDHAHGNC
Namesuccinate dehydrogenase complex flavoprotein subunit AHGNC
NCBI Gene ID6389NCBI Gene
HGNC IDHGNC:10680HGNC
EnsemblENSG00000073578NCBI Gene
AliasesCMD1GG, FP, MC2DN1, NDAXOA, PGL5, PPGL5, SDH1, SDH2, SDHFNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P31040Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial6645Ensembl, GeneID, HGNCUniProt

Patents 73

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-192416P31040Espacenet
JP 2025517970 A2025-06-122416P31040Espacenet
JP 2024123008 A2024-09-108574P31040Espacenet
US 11860162 B22024-01-021148P31040Espacenet
JP 2023541632 A2023-10-036P31040Espacenet
US 11694765 B22023-07-04156P31040Espacenet
US 11676731 B22023-06-1390P31040Espacenet
US 11446398 B22022-09-2084758P31040Espacenet
JP 2022524081 A2022-04-27187729P31040Espacenet
JP 2021533787 A2021-12-0990P31040Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 2521

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant442,025NIH's project files
P30CA016672Cancer Center Support Grant192,025NIH's project files
P30CA006927Comprehensive Cancer Center Program at Fox Chase122,025NIH's project files
R01NS083726Personalized Functional Genomics for Mitochondrial Encephalopathy Gene Discovery112,025NIH's project files
ZIABC011286Therapeutic targets and novel anticancer agents for endocrine cancers92,025NIH's project files
P30CA042014Cancer Center Support Grant82,025NIH's project files
P30CA013696Cancer Center Support Grant72,025NIH's project files
P30CA016056Roswell Park Cancer Center Support Grant72,025NIH's project files
P30CA054174Mays Cancer Center at UT Health SA72,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award72,025NIH's project files

Papers 4997

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42814798PubTator, text miningPubMed
42806009PubTator, text miningPubMed
42792729PubTator, text miningPubMed
42784129PubTator, text miningPubMed
42780368PubTator, text miningPubMed
42766034PubTator, text miningPubMed
42763556PubTator, text miningPubMed
42762005PubTator, text miningPubMed
42758527PubTator, text miningPubMed
42737428PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license