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SDHB: succinate dehydrogenase complex iron sulfur subunit B

1 protein, 30 patents, 0 drugs, 0 trials, 3,279 NIH grants and 8,337 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolSDHBHGNC
Namesuccinate dehydrogenase complex iron sulfur subunit BHGNC
NCBI Gene ID6390NCBI Gene
HGNC IDHGNC:10681HGNC
EnsemblENSG00000117118NCBI Gene
AliasesCWS2, IP, MC2DN4, PGL4, PPGL4, SDH, SDH1, SDH2, SDHIPNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P21912Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial2806Ensembl, GeneID, HGNCUniProt

Patents 30

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1465703P21912Espacenet
EP 4650780 A22025-11-199638P21912Espacenet
JP 2025147176 A2025-10-0611750P21912Espacenet
JP 2025529142 A2025-09-047645P21912Espacenet
US 12371689 B22025-07-297645P21912Espacenet
JP 2025517970 A2025-06-129638P21912Espacenet
JP 2025028160 A2025-02-2811750P21912Espacenet
KR 1020250010750 A2025-01-2111750P21912Espacenet
JP 2024109657 A2024-08-1411757P21912Espacenet
JP 2023541632 A2023-10-037P21912Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 3279

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant582,025NIH's project files
ZIABC011028Clinical Studies of the Molecular Genetic Basis of Kidney Cancer402,025NIH's project files
ZIABC011038Molecular Therapeutics of Kidney Cancer: VHL Gene and Fumarate Hydratase Gene392,025NIH's project files
P30CA016672Cancer Center Support Grant362,025NIH's project files
ZIDBC011089Clinical Nursing and Data Management Core342,025NIH's project files
ZIABC011043Molecular Therapeutics of Kidney Cancer: MET Gene and BHD Gene282,025NIH's project files
P30CA006927Comprehensive Cancer Center Program at Fox Chase172,025NIH's project files
P30CA054174Mays Cancer Center at UT Health SA152,025NIH's project files
ZIESC000853Translational Surgical Pathology142,025NIH's project files
P30CA016056Roswell Park Cancer Center Support Grant132,025NIH's project files

Papers 8337

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42822959PubTator, text miningPubMed
42814798PubTator, text miningPubMed
42813377PubTator, text miningPubMed
42806167PubTator, text miningPubMed
42804417PubTator, text miningPubMed
42804134PubTator, text miningPubMed
42769343PubTator, text miningPubMed
42760995PubTator, text miningPubMed
42758527PubTator, text miningPubMed
42737989PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license