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SELE: selectin E

1 protein, 76 patents, 4 drugs, 14 trials, 8,046 NIH grants and 19,809 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolSELEHGNC
Nameselectin EHGNC
NCBI Gene ID6401NCBI Gene
HGNC IDHGNC:10718HGNC
EnsemblENSG00000007908NCBI Gene
AliasesCD62E, ELAM, ELAM1, ESEL, LECAM2, selectin-eNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P16581E-selectin61017Ensembl, GeneID, HGNCUniProt

Patents 76

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4694905 A12026-02-181P16581Espacenet
JP 2026004568 A2026-01-1462856P16581Espacenet
JP 2026500455 A2026-01-074P16581Espacenet
EP 4650780 A22025-11-195924P16581Espacenet
EP 4641201 A22025-10-295652P16581Espacenet
JP 2025529142 A2025-09-043883P16581Espacenet
EP 4608463 A12025-09-034P16581Espacenet
WO 2025176817 A12025-08-2840P16581Espacenet
EP 4606910 A12025-08-2740P16581Espacenet
US 12371689 B22025-07-293883P16581Espacenet

Drugs 4

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
BIMOSIAMOSECHEMBL1215923Selectin inhibitorINHIBITORChEMBL
CDP-850CHEMBL2109486Selectin E inhibitorINHIBITORChEMBL
RIVIPANSELCHEMBL3707446Selectin E antagonistANTAGONISTChEMBL
UPROLESELANCHEMBL3989971Selectin E antagonistANTAGONISTChEMBL

Trials 14

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT05569512UPROLESELANPHASE1ClinicalTrials.gov
NCT05146739UPROLESELANPHASE1ClinicalTrials.gov
NCT05057221UPROLESELANPHASE1/PHASE22023-07-10ClinicalTrials.gov
NCT05054543UPROLESELANPHASE3ClinicalTrials.gov
NCT04964505UPROLESELANPHASE1ClinicalTrials.gov
NCT04848974UPROLESELANPHASE1/PHASE22025-10-20ClinicalTrials.gov
NCT04839341UPROLESELANPHASE1ClinicalTrials.gov
NCT03701308UPROLESELANPHASE2/PHASE32026-01-21ClinicalTrials.gov
NCT03616470UPROLESELANPHASE3ClinicalTrials.gov
NCT02811822UPROLESELANPHASE1ClinicalTrials.gov

NIH grants 8046

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
U19AG051426Integrative Pathways to Health and Illness342,025NIH's project files
P30CA016672Cancer Center Support Grant252,025NIH's project files
P30CA008748Cancer Center Support Grant222,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award192,025NIH's project files
R01HL103411Systems Biology of Glycosylation162,025NIH's project files
P30CA016056Roswell Park Cancer Center Support Grant132,025NIH's project files
P30CA044579University of Virginia Cancer Center Support Grant122,025NIH's project files
ZIAHD002400The Role Of Subclinical Infection And Cytokines In Preterm Parturition112,025NIH's project files
P30DK040561Boston Area Nutrition Obesity Research Center (NORC)102,025NIH's project files
P30DK043351Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital92,025NIH's project files

Papers 19809

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42818161PubTator, text miningPubMed
42806711PubTator, text miningPubMed
42794985PubTator, text miningPubMed
42770272PubTator, text miningPubMed
42759301PubTator, text miningPubMed
42747007PubTator, text miningPubMed
42737559PubTator, text miningPubMed
42728683PubTator, text miningPubMed
42717131PubTator, text miningPubMed
42698909PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license