Gene · 64109
CRLF2: cytokine receptor like factor 2
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. CRLF2: cytokine receptor like factor 2. Genes, record 64109. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/64109
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q9HC73 | Cytokine receptor-like factor 2 | 371 | 2 | Ensembl, GeneID, HGNC |
Source UniProt
Patents99
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4791773 A1 | 2026-08-19 | 70 | Q9HC73 | Espacenet |
| EP 4791783 A1 | 2026-08-19 | 70 | Q9HC73 | Espacenet |
| EP 4791792 A1 | 2026-08-19 | 70 | Q9HC73 | Espacenet |
| JP 2026094137 A | 2026-06-09 | 4 | Q9HC73 | Espacenet |
| JP 2026000906 A | 2026-01-06 | 65 | Q9HC73 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 10471 | Q9HC73 | Espacenet |
| JP 2025532685 A | 2025-10-01 | 36 | Q9HC73 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 1123 | Q9HC73 | Espacenet |
| EP 4590719 A1 | 2025-07-30 | 36 | Q9HC73 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 1123 | Q9HC73 | Espacenet |
1 to 10 of 99
See all 99 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,341
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | CRLF2 papers | Newest fiscal year |
|---|---|---|---|
| P30CA021765 | Cancer Center Support Grant (CCSG) | 59 | 2025 |
| U10CA180886 | COG NCTN Network Group Operations Center - Year 11 STAR Act MCI and PEC Supplement | 26 | 2025 |
| U10CA180899 | Children's Oncology Group Statistics and Data Center | 23 | 2025 |
| R35CA197695 | Translating genomic discoveries to improved outcomes for high risk acute leukemia | 21 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 20 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 17 | 2025 |
| ZIAHL005409 | IL-2 Family Cytokines and their Receptors--Biology of the IL-7/TSLP Systems | 14 | 2025 |
| U19AI070235 | Epithelial Genes in Allergic Inflammation | 12 | 2025 |
| T32CA128583 | Research Training in Childhood Cancer | 11 | 2025 |
| P30DK078392 | Digestive Health Center (DHC): Bench to Bedside Research in Pediatric Digestive Disease | 10 | 2025 |
1 to 10 of 1,341Source NIH's project files
See all 1,341 nih grantsPapers2,232
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Pediatric-inspired therapy and blinatumomab consolidation improve outcomes in young adults with Philadelphia-like acute lymphoblastic leukemia. | Haematologica | 2026 | 42687815 | PubTator, text mining | PubMed |
| Comprehensive genetic characterization of adult BCR::ABL1-negative B-ALL by optical genome mapping and targeted NGS. | Blood Adv | 2026 | 42664485 | PubTator, text mining | PubMed |
| Phosgene inhalation injury in mice: Modeling human pathophysiology, biomarker discovery, and therapeutic target identification. | Toxicol Appl Pharmacol | 2026 | 42575345 | PubTator, text mining | PubMed |
| Genomic profiling of Mexican patients with B-cell precursor acute lymphoblastic leukemia reveals clinically significant somatic and potential germline variants. | J Pathol Clin Res | 2026 | 42552995 | PubTator, text mining | PubMed |
| TSLP impairs mucociliary transport by inhibiting JAK signaling in both central and peripheral airways. | Pflugers Arch | 2026 | 42547653 | PubTator, text mining | PubMed |
| BACH1 meets its match: Heme licenses BACH1 destruction to tune ferroptosis. | Cell Chem Biol | 2026 | 42462695 | PubTator, text mining | PubMed |
| [Clinical features of CRLF2 overexpression in pediatric B-cell acute lymphoblastic leukemia]. | Zhongguo Dang Dai Er Ke Za Zhi | 2026 | 42457326 | PubTator, text mining | PubMed |
| Clinical features and initial treatment outcomes of pediatric B-cell acute lymphoblastic leukemia with P2RY8::CRLF2 fusion positivity: a case series. | Transl Pediatr | 2026 | 42433937 | PubTator, text mining | PubMed |
| Native Mass Spectrometry Analysis of Cullin-RING Ubiquitin E3 Ligase Complexes in the Context of Targeted Protein Degradation. | Anal Chem | 2026 | 42378227 | PubTator, text mining | PubMed |
| Combination of p-STAT5, CRLF2 and copy number alterations as a potential indicator of a high-risk subgroup of acute lymphoblastic leukemia. | Discov Oncol | 2026 | 42334675 | PubTator, text mining | PubMed |
1 to 10 of 2,232
See all 2,232 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/64109
GET https://conductscience.org/api/genes/v1/64109/patents?page=2