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Gene · 64170

CARD9: caspase recruitment domain family member 9

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CARD9: caspase recruitment domain family member 9. Genes, record 64170. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/64170

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Gene

Symbol
CARD9
HGNC
Name
caspase recruitment domain family member 9
HGNC
NCBI Gene ID
64170
NCBI Gene
HGNC ID
HGNC:16391
HGNC
Ensembl
ENSG00000187796
NCBI Gene
Aliases
CANDF2, IMD103, hCARD9
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9H257Caspase recruitment domain-containing protein 95368Ensembl, GeneID, HGNC

Source UniProt

Patents35

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4774293 A12026-07-1566Q9H257Espacenet
JP 2026004568 A2026-01-1440236Q9H257Espacenet
EP 4640849 A22025-10-291347Q9H257Espacenet
EP 4641201 A22025-10-299242Q9H257Espacenet
JP 2025524002 A2025-07-2511Q9H257Espacenet
JP 2025519096 A2025-06-241347Q9H257Espacenet
JP 2025517969 A2025-06-129242Q9H257Espacenet
KR 1020250039465 A2025-03-2011Q9H257Espacenet
WO 2025049272 A12025-03-061Q9H257Espacenet
JP 2024023699 A2024-02-2111Q9H257Espacenet

1 to 10 of 35

See all 35 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,339

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCARD9 papersNewest fiscal year
P30DK043351Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital322025
ZIAAI001175Immunopathogenesis of Fungal Infections212025
R01AI127564Genome-wide search for inborn errors of IL-17 immunity underlying chronic mucocutaneous candidiasis142025
U01DK062432Montreal-Boston Collaborative GRC142025
U01DK062422Mount Sinai NYC Genetics Research Center: Multi-omic integration across data-types, cell niches and populations122025
U01DK062423Genomic and Immunologic Characterization of Inflammatory Bowel Disease and its Phenotypes112025
ZIAAI000647Genes And Gene Products As Immunoadjuvants112025
R37DE022550Host and Fungal Regulation of Type 17 Immunity to Oral Candidiasis102025
U01DK062413Determining genomic and host-environment contributions to IBD phenotypes102025
U01DK062431IBD Gene Mapping by Clinical and Population Subset102025

1 to 10 of 1,339Source NIH's project files

See all 1,339 nih grants

Papers1,898

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Probable invasive Alternaria rhinosinusitis in a previously healthy patient diagnosed with heterozygous CARD9 deficiency and combined immunodeficiency.IDCases202642819743PubTator, text miningPubMed
Longxue tongluo capsule enhances ischemic stroke recovery via microbiota-metabolite-gene interactions.Metab Brain Dis202642804018PubTator, text miningPubMed
Microbiota-derived self-adjuvanting exopolysaccharide-based codelivery system for potent cancer immunotherapy.Mater Today Bio202642781103PubTator, text miningPubMed
Genetic Regulation of DNA Methylation and Its Mediating Role in Blood Pressure: A Genome-Wide Twin Study.MedComm (2020)202642756691PubTator, text miningPubMed
Multi-omics and machine learning identify ALOX5 as a ferroptosis-associated driver of epithelial barrier dysfunction in chronic rhinosinusitis with nasal polyps.World Allergy Organ J202642751055PubTator, text miningPubMed
The impact for causal associations between common diseases and inflammatory bowel disease: a disease-wide bidirectional Mendelian randomization study.Inflamm Res202642700258PubTator, text miningPubMed
Computational insights into the regulatory role and functional significance of NOTCH1 intronic SNP rs3124599 and its link to NPC.Comput Biol Chem202642685632PubTator, text miningPubMed
Shared genetic architecture between Crohn's disease and IgA nephropathy: implications for a gut-immune-kidney axis.Front Immunol202642614547PubTator, text miningPubMed
Osteocyte-specific gasdermin D deletion accelerates osteoarthritis via promoting subchondral inflammation and remodeling.Bone Res202642521692PubTator, text miningPubMed
Fungal Infections in Disorders of Inborn Errors of Immunity.Clin Rev Allergy Immunol202642461459PubTator, text miningPubMed

1 to 10 of 1,898

See all 1,898 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/64170

GET https://conductscience.org/api/genes/v1/64170/patents?page=2