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Gene · 6422

SFRP1: secreted frizzled related protein 1

11 sourcesgene-search-2026-11-11-0.1.0

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ConductScience Library. SFRP1: secreted frizzled related protein 1. Genes, record 6422. Release gene-search-2026-11-11-0.1.0, 11 Nov 2026. https://conductscience.org/library/genes/6422

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Gene

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

Symbol
SFRP1
HGNC
Name
secreted frizzled related protein 1
HGNC
NCBI Gene ID
6422
NCBI Gene
HGNC ID
HGNC:10776
HGNC
Ensembl
ENSG00000104332
NCBI Gene
Aliases
FRP, FRP-1, FRP1, FrzA, SARP2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q8N474Secreted frizzled-related protein 13140Ensembl, GeneID, HGNC

Source UniProt

Patents76

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4698208 A22026-02-2513Q8N474Espacenet
EP 4650780 A22025-11-19482Q8N474Espacenet
JP 2025147176 A2025-10-0612155Q8N474Espacenet
JP 2025529142 A2025-09-047697Q8N474Espacenet
US 12371689 B22025-07-297697Q8N474Espacenet
JP 2025517970 A2025-06-12482Q8N474Espacenet
JP 2025028160 A2025-02-2812155Q8N474Espacenet
KR 1020250010750 A2025-01-2112155Q8N474Espacenet
JP 2024123008 A2024-09-108313Q8N474Espacenet
JP 2024123008 A2024-09-108314Q8N474Espacenet

1 to 10 of 76

See all 76 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,350

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal year
P30CA016672Cancer Center Support Grant272025
P30CA008748Cancer Center Support Grant122025
P30CA006973Regional Oncology Research Center112025
R01CA159859Dysregulation of the Core Binding Factor Complex Inhibits Differentiation and Drives Group 4 Medulloblastoma102025
P30CA014089University of Southern California Norris Comprehensive Cancer Center Support Grant (CCSG)82025
P30CA015083Mayo Clinic Comprehensive Cancer Center Support Grant72025
P30CA062203Cancer Center Support Grant72025
P30CA016087Cancer Center Support Grant62025
P30ES010126UNC Center for Environmental Health and Susceptibility62025
P30CA006927Comprehensive Cancer Center Program at Fox Chase52025

1 to 10 of 2,350Source NIH's project files

See all 2,350 nih grants

Papers4,318

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42774843PubTator, text miningPubMed
42620201PubTator, text miningPubMed
42614535PubTator, text miningPubMed
42610667PubTator, text miningPubMed
42586918PubTator, text miningPubMed
42574754PubTator, text miningPubMed
42569572PubTator, text miningPubMed
42537335PubTator, text miningPubMed
42499581PubTator, text miningPubMed
42497285PubTator, text miningPubMed

1 to 10 of 4,318

See all 4,318 papers

Sources 11

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNone stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GeneNone named. Public domain as US government information
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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The record and each of its lists are JSON, twenty rows a page. No key.

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