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Gene · 64241

ABCG8: ATP binding cassette subfamily G member 8

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ABCG8: ATP binding cassette subfamily G member 8. Genes, record 64241. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/64241

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Gene

Symbol
ABCG8
HGNC
Name
ATP binding cassette subfamily G member 8
HGNC
NCBI Gene ID
64241
NCBI Gene
HGNC ID
HGNC:13887
HGNC
Ensembl
ENSG00000143921
NCBI Gene
Aliases
GBD4, STSL, STSL1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9H221ATP-binding cassette sub-family G member 86738Ensembl, GeneID, HGNC

Source UniProt

Patents29

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4774294 A12026-07-15288Q9H221Espacenet
JP 2026067851 A2026-04-21415Q9H221Espacenet
JP 2026004568 A2026-01-1438509Q9H221Espacenet
EP 4640849 A22025-10-29348Q9H221Espacenet
EP 4641201 A22025-10-292374Q9H221Espacenet
JP 2025529142 A2025-09-04215Q9H221Espacenet
US 12371689 B22025-07-29215Q9H221Espacenet
JP 2025519096 A2025-06-24348Q9H221Espacenet
JP 2025517969 A2025-06-122374Q9H221Espacenet
JP 2025062604 A2025-04-147851Q9H221Espacenet

1 to 10 of 29

See all 29 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants897

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleABCG8 papersNewest fiscal year
R01HL072304Role of ABCG1, ABCG5 and ABCG8 in Sterol Metabolism82025
R01DK113625Contributions of Hepatic and Intestinal Pathways to Cholesterol Excretion52025
P30DK063491Diabetes Research Center (DRC)42025
R01DK062370Identifying Genes for Type 2 Diabetes: FUSION42025
ZIAHG000024Genetic analysis of type II diabetes42025
ZIAHL006170Cardiovascular Genomics and Bioinformatics projects42025
P30CA034196Cancer Center Support (CORE) Grant32025
P30ES005022Rutgers Center for Environmental Exposure and Disease (CEED)32025
R01HL142711Whole genome sequences in ethnically diverse individuals to comprehensively characterize the genetic mechanisms of dyslipidemias32025
ZIACP010121Molecular Epidemiology Studies of Occupational and Environmental Exposures32025

1 to 10 of 897Source NIH's project files

See all 897 nih grants

Papers1,622

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Sitosterolemia presenting as unexplained cytopenias: hematologic manifestations and genetic spectrum.Blood Res202642825986PubTator, text miningPubMed
Reverse Cascade Genetic Screening for Revealing New Cases of Familial Hypercholesterolemia in Russia: Pilot Project.Front Biosci (Schol Ed)202642812038PubTator, text miningPubMed
Multilevel genome-wide analysis reveals shared genetic architecture between acute pancreatitis and body fat distribution.World J Emerg Med202642807309PubTator, text miningPubMed
Hematologic manifestations of sitosterolemia: Phenotypic spectrum and long-term outcomes in seven genetically confirmed patients.Blood Cells Mol Dis202642743615PubTator, text miningPubMed
Combined Metabolomic and Transcriptomic Analysis Identifies Metabolic Signatures and Networks Associated with Semen Quality in Geese.Animals (Basel)202642738551PubTator, text miningPubMed
Phenotypic and Genotypic Landscape of Sitosterolemia in China: Including a Rare Case With Nephronophthisis.Mol Genet Genomic Med202642734259PubTator, text miningPubMed
Thermosonication-induced structural remodeling of faba bean protein: Improved functionality, digestibility, and cholesterol metabolism regulation for cardiovascular health.Ultrason Sonochem202642721809PubTator, text miningPubMed
Sitosterolemia in pregnancy: A rare lipid disorder and its obstetric management.Obstet Med202642688270PubTator, text miningPubMed
Genome-Wide Association of Genetic Variants with Intestinal Cholesterol Absorption Markers in a European Population.Nutrients202642654259PubTator, text miningPubMed
Sitosterolemia: evolving strategies for earlier diagnosis.Curr Opin Lipidol202642636792PubTator, text miningPubMed

1 to 10 of 1,622

See all 1,622 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/64241

GET https://conductscience.org/api/genes/v1/64241/patents?page=2