Gene · 64241
ABCG8: ATP binding cassette subfamily G member 8
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. ABCG8: ATP binding cassette subfamily G member 8. Genes, record 64241. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/64241
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q9H221 | ATP-binding cassette sub-family G member 8 | 673 | 8 | Ensembl, GeneID, HGNC |
Source UniProt
Patents29
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4774294 A1 | 2026-07-15 | 288 | Q9H221 | Espacenet |
| JP 2026067851 A | 2026-04-21 | 415 | Q9H221 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 38509 | Q9H221 | Espacenet |
| EP 4640849 A2 | 2025-10-29 | 348 | Q9H221 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 2374 | Q9H221 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 215 | Q9H221 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 215 | Q9H221 | Espacenet |
| JP 2025519096 A | 2025-06-24 | 348 | Q9H221 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 2374 | Q9H221 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 7851 | Q9H221 | Espacenet |
1 to 10 of 29
See all 29 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants897
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | ABCG8 papers | Newest fiscal year |
|---|---|---|---|
| R01HL072304 | Role of ABCG1, ABCG5 and ABCG8 in Sterol Metabolism | 8 | 2025 |
| R01DK113625 | Contributions of Hepatic and Intestinal Pathways to Cholesterol Excretion | 5 | 2025 |
| P30DK063491 | Diabetes Research Center (DRC) | 4 | 2025 |
| R01DK062370 | Identifying Genes for Type 2 Diabetes: FUSION | 4 | 2025 |
| ZIAHG000024 | Genetic analysis of type II diabetes | 4 | 2025 |
| ZIAHL006170 | Cardiovascular Genomics and Bioinformatics projects | 4 | 2025 |
| P30CA034196 | Cancer Center Support (CORE) Grant | 3 | 2025 |
| P30ES005022 | Rutgers Center for Environmental Exposure and Disease (CEED) | 3 | 2025 |
| R01HL142711 | Whole genome sequences in ethnically diverse individuals to comprehensively characterize the genetic mechanisms of dyslipidemias | 3 | 2025 |
| ZIACP010121 | Molecular Epidemiology Studies of Occupational and Environmental Exposures | 3 | 2025 |
1 to 10 of 897Source NIH's project files
See all 897 nih grantsPapers1,622
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Sitosterolemia presenting as unexplained cytopenias: hematologic manifestations and genetic spectrum. | Blood Res | 2026 | 42825986 | PubTator, text mining | PubMed |
| Reverse Cascade Genetic Screening for Revealing New Cases of Familial Hypercholesterolemia in Russia: Pilot Project. | Front Biosci (Schol Ed) | 2026 | 42812038 | PubTator, text mining | PubMed |
| Multilevel genome-wide analysis reveals shared genetic architecture between acute pancreatitis and body fat distribution. | World J Emerg Med | 2026 | 42807309 | PubTator, text mining | PubMed |
| Hematologic manifestations of sitosterolemia: Phenotypic spectrum and long-term outcomes in seven genetically confirmed patients. | Blood Cells Mol Dis | 2026 | 42743615 | PubTator, text mining | PubMed |
| Combined Metabolomic and Transcriptomic Analysis Identifies Metabolic Signatures and Networks Associated with Semen Quality in Geese. | Animals (Basel) | 2026 | 42738551 | PubTator, text mining | PubMed |
| Phenotypic and Genotypic Landscape of Sitosterolemia in China: Including a Rare Case With Nephronophthisis. | Mol Genet Genomic Med | 2026 | 42734259 | PubTator, text mining | PubMed |
| Thermosonication-induced structural remodeling of faba bean protein: Improved functionality, digestibility, and cholesterol metabolism regulation for cardiovascular health. | Ultrason Sonochem | 2026 | 42721809 | PubTator, text mining | PubMed |
| Sitosterolemia in pregnancy: A rare lipid disorder and its obstetric management. | Obstet Med | 2026 | 42688270 | PubTator, text mining | PubMed |
| Genome-Wide Association of Genetic Variants with Intestinal Cholesterol Absorption Markers in a European Population. | Nutrients | 2026 | 42654259 | PubTator, text mining | PubMed |
| Sitosterolemia: evolving strategies for earlier diagnosis. | Curr Opin Lipidol | 2026 | 42636792 | PubTator, text mining | PubMed |
1 to 10 of 1,622
See all 1,622 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/64241
GET https://conductscience.org/api/genes/v1/64241/patents?page=2