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SRSF1: serine and arginine rich splicing factor 1

1 protein, 62 patents, 0 drugs, 0 trials, 3,169 NIH grants and 5,528 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolSRSF1HGNC
Nameserine and arginine rich splicing factor 1HGNC
NCBI Gene ID6426NCBI Gene
HGNC IDHGNC:10780HGNC
EnsemblENSG00000136450NCBI Gene
AliasesASF, MGC5228, NEDFBA, SF2, SF2p33, SFRS1, SRp30aNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q07955Serine/arginine-rich splicing factor 124810Ensembl, GeneID, HGNCUniProt

Patents 62

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1463072Q07955Espacenet
EP 4650780 A22025-11-191722Q07955Espacenet
JP 2025526762 A2025-08-1560Q07955Espacenet
JP 2025517970 A2025-06-121722Q07955Espacenet
KR 1020250048560 A2025-04-0960Q07955Espacenet
EP 4518908 A22025-03-122Q07955Espacenet
US 12186353 B22025-01-0715Q07955Espacenet
KR 1020230131703 A2023-09-1413Q07955Espacenet
US 11628159 B22023-04-187Q07955Espacenet
US 11446398 B22022-09-2077734Q07955Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 3169

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P01CA013106Targeting Transcription and Splicing in Cancer442,025NIH's project files
R01GM042699Biochemistry of Pre-mRNA Splicing312,025NIH's project files
P30CA008748Cancer Center Support Grant282,025NIH's project files
P30CA045508CSHL Cancer Center Support Grant202,025NIH's project files
P30CA016672Cancer Center Support Grant162,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)162,025NIH's project files
ZIASC010357Gene Expression and Post-Transcriptional Regulation of DNA Tumor Viruses122,025NIH's project files
P30MH092177Comprehensive NeuroHIV Center102,025NIH's project files
ZIAAG000741Roles Of DNA Helicases In Pathways Required For Maintenance Of Genomic Stability102,025NIH's project files
R01HL128239Genetic and molecular basis for SRSF2 mutations in myelodysplasia92,025NIH's project files

Papers 5528

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42818787PubTator, text miningPubMed
42818347PubTator, text miningPubMed
42810629PubTator, text miningPubMed
42806041PubTator, text miningPubMed
42768744PubTator, text miningPubMed
42764753PubTator, text miningPubMed
42664534PubTator, text miningPubMed
42607060PubTator, text miningPubMed
42587760PubTator, text miningPubMed
42546792PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license