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SRSF2: serine and arginine rich splicing factor 2

1 protein, 55 patents, 0 drugs, 0 trials, 3,042 NIH grants and 6,067 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolSRSF2HGNC
Nameserine and arginine rich splicing factor 2HGNC
NCBI Gene ID6427NCBI Gene
HGNC IDHGNC:10783HGNC
EnsemblENSG00000161547NCBI Gene
AliasesPR264, SC-35, SC35, SFRS2, SFRS2A, SRp30bNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q01130Serine/arginine-rich splicing factor 22214Ensembl, GeneID, HGNCUniProt

Patents 55

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1463090Q01130Espacenet
EP 4650780 A22025-11-197734Q01130Espacenet
EP 4641202 A22025-10-295313Q01130Espacenet
JP 2025517970 A2025-06-127734Q01130Espacenet
KR 1020250017231 A2025-02-045313Q01130Espacenet
JP 2024009871 A2024-01-2345Q01130Espacenet
US 11694765 B22023-07-04254Q01130Espacenet
US 11694765 B22023-07-04308Q01130Espacenet
US 11446398 B22022-09-2077760Q01130Espacenet
US 11446398 B22022-09-2077761Q01130Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 3042

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant1052,025NIH's project files
P30CA016672Cancer Center Support Grant862,025NIH's project files
R01HL128239Genetic and molecular basis for SRSF2 mutations in myelodysplasia352,025NIH's project files
P50CA171963Specialized Program of Research Excellence (SPORE) in Leukemia212,025NIH's project files
P01CA013106Targeting Transcription and Splicing in Cancer202,025NIH's project files
P30CA016058Cancer Center Support Grant202,025NIH's project files
P30CA045508CSHL Cancer Center Support Grant172,025NIH's project files
P01CA108671Myeloproliferative Neoplasms-Research Consortium162,025NIH's project files
P30CA015704Cancer Center Support Grant162,025NIH's project files
R01GM042699Biochemistry of Pre-mRNA Splicing152,025NIH's project files

Papers 6067

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42826160PubTator, text miningPubMed
42806052PubTator, text miningPubMed
42796004PubTator, text miningPubMed
42773214PubTator, text miningPubMed
42743920PubTator, text miningPubMed
42736327PubTator, text miningPubMed
42733996PubTator, text miningPubMed
42728663PubTator, text miningPubMed
42726641PubTator, text miningPubMed
42724865PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license