Gene · 6428
SRSF3: serine and arginine rich splicing factor 3
12 sourcesgene-search-2026-11-11-0.2.0
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ConductScience Library. SRSF3: serine and arginine rich splicing factor 3. Genes, record 6428. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6428
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Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P84103 | Serine/arginine-rich splicing factor 3 | 164 | 3 | Ensembl, GeneID, HGNC |
Source UniProt
Patents43
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 63094 | P84103 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 9361 | P84103 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 9361 | P84103 | Espacenet |
| JP 2025038035 A | 2025-03-18 | 4444 | P84103 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 36497 | P84103 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 36499 | P84103 | Espacenet |
| EP 4461818 A2 | 2024-11-13 | 36497 | P84103 | Espacenet |
| EP 4461818 A2 | 2024-11-13 | 36499 | P84103 | Espacenet |
| US 12134655 B2 | 2024-11-05 | 4444 | P84103 | Espacenet |
| JP 2023058610 A | 2023-04-25 | 36497 | P84103 | Espacenet |
1 to 10 of 43
See all 43 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,293
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | SRSF3 papers | Newest fiscal year |
|---|---|---|---|
| ZIASC010357 | Gene Expression and Post-Transcriptional Regulation of DNA Tumor Viruses | 19 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 13 | 2025 |
| P01CA013106 | Targeting Transcription and Splicing in Cancer | 12 | 2025 |
| P30CA045508 | CSHL Cancer Center Support Grant | 10 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 7 | 2025 |
| P30CA034196 | Cancer Center Support (CORE) Grant | 7 | 2025 |
| P30DK063491 | Diabetes Research Center (DRC) | 7 | 2025 |
| R01HL128239 | Genetic and molecular basis for SRSF2 mutations in myelodysplasia | 7 | 2025 |
| P30CA062203 | Cancer Center Support Grant | 6 | 2025 |
| P30CA015704 | Cancer Center Support Grant | 5 | 2025 |
1 to 10 of 1,293Source NIH's project files
See all 1,293 nih grantsPapers2,106
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Targeting the KIFC1-SRSF3-PKM Axis Suppresses Cervical Cancer Glycolysis and Enhances Radiosensitivity. | J Cell Mol Med | 2026 | 42764482 | PubTator, text mining | PubMed |
| Co-occurrence of bronchiolar adenoma and lung adenocarcinoma: a study of nine cases revealing distinct clonal origins via integrated histologic, immunophenotypic and molecular analysis. | Hum Pathol | 2026 | 42722080 | PubTator, text mining | PubMed |
| Disease-driven post-transcriptional alterations and alternative splicing in podocytes in focal segmental glomerulosclerosis. | EMBO Mol Med | 2026 | 42595826 | PubTator, text mining | PubMed |
| Loss of cellular RNA homeostasis contributes to MDA5 activation during virus infection. | Nat Immunol | 2026 | 42581186 | PubTator, text mining | PubMed |
| C3G Downregulation Enhances Stemness in Glioblastoma Cells by Promoting PKM2 Upregulation. | Int J Biol Sci | 2026 | 42524459 | PubTator, text mining | PubMed |
| The role of splicing factor SRSF3 in cancer progression: Mechanisms, biomarkers, and therapeutic implications. | Transl Oncol | 2026 | 42462457 | PubTator, text mining | PubMed |
| Correction: Regulation of oncogenic C-terminal truncated p53β protein isoform expression by SRSF3-UPF1 splicing and surveillance axis. | Cell Biosci | 2026 | 42437955 | PubTator, text mining | PubMed |
| Coordinated DNA 5-mC and RNA m5C methylation epigenetically regulates MZF1 splice variants to drive EGFR-TKI resistance. | Exp Mol Med | 2026 | 42380284 | PubTator, text mining | PubMed |
| Splicing of ultraconserved poison exons controls mitotic fidelity and stem cell viability. | bioRxiv | 2026 | 42239477 | PubTator, text mining | PubMed |
| Integrative epidemiological and experimental evidence implicates CCNA2-associated macrophage-hepatocyte crosstalk in dimethyl phosphate exposure-associated NAFLD. | Environ Pollut | 2026 | 42235667 | PubTator, text mining | PubMed |
1 to 10 of 2,106
See all 2,106 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
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The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/6428
GET https://conductscience.org/api/genes/v1/6428/patents?page=2