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Gene · 6430

SRSF5: serine and arginine rich splicing factor 5

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. SRSF5: serine and arginine rich splicing factor 5. Genes, record 6430. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6430

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Gene

Symbol
SRSF5
HGNC
Name
serine and arginine rich splicing factor 5
HGNC
NCBI Gene ID
6430
NCBI Gene
HGNC ID
HGNC:10787
HGNC
Ensembl
ENSG00000100650
NCBI Gene
Aliases
HRS, SFRS5, SRP40
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q13243Serine/arginine-rich splicing factor 52720Ensembl, GeneID, HGNC

Source UniProt

Patents34

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1463098Q13243Espacenet
JP 2026004568 A2026-01-1463100Q13243Espacenet
JP 2026004568 A2026-01-1463101Q13243Espacenet
EP 4650780 A22025-11-1911134Q13243Espacenet
EP 4641201 A22025-10-2911590Q13243Espacenet
EP 4641202 A22025-10-295902Q13243Espacenet
JP 2025517969 A2025-06-1211590Q13243Espacenet
JP 2025517970 A2025-06-1211134Q13243Espacenet
KR 1020250017231 A2025-02-045902Q13243Espacenet
US 11446398 B22022-09-2077774Q13243Espacenet

1 to 10 of 34

See all 34 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,247

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleSRSF5 papersNewest fiscal year
R01GM042699Biochemistry of Pre-mRNA Splicing82025
P30CA008748Cancer Center Support Grant62025
P30CA045508CSHL Cancer Center Support Grant62025
ZIAHD001607Protein Trafficking In The Endosomal-Lysosomal System52025
P01CA013106Targeting Transcription and Splicing in Cancer42025
R01HL128239Genetic and molecular basis for SRSF2 mutations in myelodysplasia42025
P30CA006927Comprehensive Cancer Center Program at Fox Chase32025
P30CA014051Cancer Center Support (Core) Grant32025
P30CA014520UW Comprehensive Cancer Center Support32025
P30CA034196Cancer Center Support (CORE) Grant32025

1 to 10 of 1,247Source NIH's project files

See all 1,247 nih grants

Papers1,509

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Transcriptome-based identification and experimental validation of a key gene in Alzheimer's disease using dermal fibroblasts.J Alzheimers Dis202642024084PubTator, text miningPubMed
The biased adenosine-rich content of the HIV-1 genome serves as a molecular signature that facilitates efficient packaging.Proc Natl Acad Sci U S A202641926539PubTator, text miningPubMed
[Expression, Prognostic and Functional Analysis of SRSF Family Proteins in Non-small Cell Lung Cancer].Zhongguo Fei Ai Za Zhi202641916911PubTator, text miningPubMed
CHAtRF Modulates Cardiac Hypertrophy via SRSF5-Dependent Regulation of Psmg4 Alternative Splicing.Research (Wash D C)202641907183PubTator, text miningPubMed
Pathogenic Analysis of Two SLC22A5 Variants That Alter RNA Splicing in Patients with Primary Carnitine Deficiency.Int J Neonatal Screen202641892025PubTator, text miningPubMed
Unveiling biomarkers of telitacicept's efficacy in SLE treatment through proteomics and metabolomics.Front Immunol202641859090PubTator, text miningPubMed
Exosomal circ0000549 promotes MNNG‑induced gastric cancer through miR‑15b‑5p/KIF1B.Int J Mol Med202641789656PubTator, text miningPubMed
Genetic correlation-guided mega-analysis of DO mice provides mechanistic insight and candidate genes for age-related pathologies.PLoS Genet202641758904PubTator, text miningPubMed
Acid sphingomyelinase inhibition restores RPE homeostasis and photoreceptor function in preclinical Stargardt macular degeneration models.bioRxiv202641757049PubTator, text miningPubMed
SMURF1 Downregulation Highlights Its Potential Role in Breast Cancer.Int J Mol Sci202641752056PubTator, text miningPubMed

1 to 10 of 1,509

See all 1,509 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/6430

GET https://conductscience.org/api/genes/v1/6430/patents?page=2