Gene · 64324
NSD1: nuclear receptor binding SET domain protein 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. NSD1: nuclear receptor binding SET domain protein 1. Genes, record 64324. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/64324
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q96L73 | Histone-lysine N-methyltransferase, H3 lysine-36 specific | 2,696 | 4 | Ensembl, GeneID, HGNC |
Source UniProt
Patents27
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 56085 | Q96L73 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 14169 | Q96L73 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 14169 | Q96L73 | Espacenet |
| JP 2023549761 A | 2023-11-29 | 236 | Q96L73 | Espacenet |
| JP 2022141755 A | 2022-09-29 | 232 | Q96L73 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 58291 | Q96L73 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 161262 | Q96L73 | Espacenet |
| US 11136562 B2 | 2021-10-05 | 293 | Q96L73 | Espacenet |
| JP 2019054813 A | 2019-04-11 | 236520 | Q96L73 | Espacenet |
| JP 2019507586 A | 2019-03-22 | 5 | Q96L73 | Espacenet |
1 to 10 of 27
See all 27 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,401
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | NSD1 papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 37 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 21 | 2025 |
| P30CA021765 | Cancer Center Support Grant (CCSG) | 20 | 2025 |
| U10CA180899 | Children's Oncology Group Statistics and Data Center | 12 | 2025 |
| U10CA180886 | COG NCTN Network Group Operations Center - Year 11 STAR Act MCI and PEC Supplement | 11 | 2025 |
| P30CA060553 | The Robert H. Lurie Comprehensive Cancer Center | 9 | 2025 |
| P30CA016086 | Cancer Center Support Grant | 8 | 2025 |
| P30CA091842 | Cancer Center Support Grant | 8 | 2025 |
| P01CA066996 | Development of Novel Therapeutic Strategies in Human Leukemias | 7 | 2025 |
| R01AI118891 | Viral modulation of epitranscriptomic mechanisms | 6 | 2025 |
1 to 10 of 1,401Source NIH's project files
See all 1,401 nih grantsPapers2,293
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Thoracic Aortic Disease in Genetic Syndromes Beyond Established Aortopathy Genes. | medRxiv | 2026 | 42818859 | PubTator, text mining | PubMed |
| NSD Histone Methyltransferases in Solid Tumors: Biological Functions, Oncogenic Mechanisms and Therapeutic Targeting. | Int J Mol Sci | 2026 | 42794546 | PubTator, text mining | PubMed |
| Unmasked Behavioral Disturbance Following Traumatic Brain Injury in an Adult With Previously Undiagnosed Sotos Syndrome. | Cureus | 2026 | 42621581 | PubTator, text mining | PubMed |
| Sotos and Malan Syndromes in Childhood: Molecular and Clinical Findings From a Nationwide Cohort of 48 Patients. | Clin Genet | 2026 | 42618064 | PubTator, text mining | PubMed |
| Genetic Etiology and Neurodevelopmental Outcomes in Children With Craniosynostosis: A 15-Year Single-Center Retrospective Study. | J Craniofac Surg | 2026 | 42607197 | PubTator, text mining | PubMed |
| Gonocytes in Transition: Establishing the Male Germline Identity. | Adv Exp Med Biol | 2026 | 42455434 | PubTator, text mining | PubMed |
| Overcoming Therapeutic Resistance in Head and Neck Squamous Cell Carcinoma (HNSCC): The Role of Histone Methyltransferase and Demethylase Inhibitors. | Cancers (Basel) | 2026 | 42449712 | PubTator, text mining | PubMed |
| Oncogenic PIK3CA mutation enhances tumor immunogenicity through the IRF1-NLRC5-MHC-I axis in urothelial carcinoma. | J Immunother Cancer | 2026 | 42413983 | PubTator, text mining | PubMed |
| Management of Acute Myeloid Leukemia in a Dialysis-Dependent Patient: A Case Report, Literature Review, and Therapeutic Considerations. | Cureus | 2026 | 42292729 | PubTator, text mining | PubMed |
| Clinical characterization and developmental follow-up of a child with Sotos syndrome carrying a novel NSD1 variant. | BMC Pediatr | 2026 | 42286513 | PubTator, text mining | PubMed |
1 to 10 of 2,293
See all 2,293 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/64324
GET https://conductscience.org/api/genes/v1/64324/patents?page=2