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Gene · 6439

SFTPB: surfactant protein B

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. SFTPB: surfactant protein B. Genes, record 6439. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6439

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Gene

Symbol
SFTPB
HGNC
Name
surfactant protein B
HGNC
NCBI Gene ID
6439
NCBI Gene
HGNC ID
HGNC:10801
HGNC
Ensembl
ENSG00000168878
NCBI Gene
Aliases
PSP-B, SFTB3, SFTP3, SMDP1, SP-B
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P07988Pulmonary surfactant-associated protein B3819Ensembl, GeneID, HGNC

Source UniProt

Patents75

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026509256 A2026-03-1757P07988Espacenet
JP 2026027383 A2026-02-1822P07988Espacenet
JP 2026004568 A2026-01-1465907P07988Espacenet
EP 4650780 A22025-11-1911072P07988Espacenet
JP 2025533754 A2025-10-0941P07988Espacenet
JP 2025147176 A2025-10-0612173P07988Espacenet
JP 2025147176 A2025-10-0612174P07988Espacenet
JP 2025529142 A2025-09-047704P07988Espacenet
US 12405274 B22025-09-024P07988Espacenet
US 12371689 B22025-07-297704P07988Espacenet

1 to 10 of 75

See all 75 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,156

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleSFTPB papersNewest fiscal year
R01HL051177Lipid and Protein Effects on Monolayer Stability132025
R01HL095993Derivation of lung epithelia from iPS cells for advanced disease modeling132025
P30ES013508Center of Excellence in Environmental Toxicology112025
P30CA016672Cancer Center Support Grant102025
P30CA014051Cancer Center Support (Core) Grant92025
P30ES005605Environmental Health Sciences Research Center72025
R01HL149853Functional Characterization of ABCA3 Genomic Variants62025
R24HD000836Laboratory of Developmental Biology62025
T32DE007057Tissue Engineering and Regeneration62025
T32HL007427SYSTEMS APPROACHES TO THE EPIDEMIOLOGY, GENETICS AND GENOMICS OF LUNG DISEASES62025

1 to 10 of 2,156Source NIH's project files

See all 2,156 nih grants

Papers3,679

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Adulthood interstitial lung disease due to variants in surfactant related genes: A systematic review.Pulmonology202642784242PubTator, text miningPubMed
Preoperative Pulmonary Blood Flow, Cardiopulmonary Bypass, and Lung Inflammation in Children With Congenital Heart Disease: Post Hoc Analysis of a Single-Center Prospective Cohort.Pediatr Crit Care Med202642752530PubTator, text miningPubMed
Adult-Onset Interstitial Lung Disease Due to Homozygous SFTPB Variant.Lung202642747575PubTator, text miningPubMed
PM10 Exposure Impairs Differentiation and Induces Inflammation in Human Small Airway Epithelial Cells Cultured at the Air-Liquid Interface.Tuberc Respir Dis (Seoul)202642693576PubTator, text miningPubMed
Role of connexin 43 in hyperoxia-induced bronchopulmonary dysplasia and associated pulmonary hypertension.PLoS One202642636229PubTator, text miningPubMed
Route-resolved priority risks of disinfection by-products in indoor pools: the underestimated role of buccal/sublingual exposure for the public and competitive swimmers.Front Public Health202642582110PubTator, text miningPubMed
Surfactant-associated proteins perturb lipid membrane architecture: insights from nanoplasmonic sensing and differential scanning calorimetry.Analyst202642555126PubTator, text miningPubMed
Exercise-Induced Plasma Surfactant Protein B Response in Advanced Heart Failure: Relation to Exercise Limitation, Resting Invasive Hemodynamics, and Clinical Outcomes.Int J Mol Sci202642511804PubTator, text miningPubMed
Integrated hypoxia and metabolic gene signature to predict clinical outcomes and therapeutic vulnerabilities in lung adenocarcinoma.J Thorac Dis202642444878PubTator, text miningPubMed
FN-silk membrane enables alveologenesis processes and self-organization of the H441 epithelial cell line into native-like alveolar morphology.Sci Rep202642365140PubTator, text miningPubMed

1 to 10 of 3,679

See all 3,679 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/6439

GET https://conductscience.org/api/genes/v1/6439/patents?page=2