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Gene · 64422

ATG3: autophagy related 3

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ATG3: autophagy related 3. Genes, record 64422. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/64422

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Gene

Symbol
ATG3
HGNC
Name
autophagy related 3
HGNC
NCBI Gene ID
64422
NCBI Gene
HGNC ID
HGNC:20962
HGNC
Ensembl
ENSG00000144848
NCBI Gene
Aliases
APG3, APG3-LIKE, APG3L, DKFZp564M1178, FLJ22125, MGC15201, PC3-96, hApg3
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9NT62Ubiquitin-like-conjugating enzyme ATG33144Ensembl, GeneID, HGNC

Source UniProt

Patents27

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-193200Q9NT62Espacenet
JP 2025517970 A2025-06-123200Q9NT62Espacenet
JP 2025062604 A2025-04-148019Q9NT62Espacenet
US 11564998 B22023-01-315074Q9NT62Espacenet
US 11446398 B22022-09-208019Q9NT62Espacenet
JP 2022524081 A2022-04-27110990Q9NT62Espacenet
WO 2021201116 A2021-10-0730Q9NT62Espacenet
US 11078247 B22021-08-03889Q9NT62Espacenet
US 10695341 B22020-06-30113Q9NT62Espacenet
WO 2020043812 A12020-03-054Q9NT62Espacenet

1 to 10 of 27

See all 27 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,439

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleATG3 papersNewest fiscal year
R01CA126792Autophagy and Pro-metastatic Differentiation182025
R35GM131919The mechanism and regulation of autophagy102025
P30CA008748Cancer Center Support Grant92025
P30DK043351Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital92025
R01CA140964Autophagy-mediated defense against inflammation and cancer92025
P20GM121176Autophagy, Inflammation and Metabolism (AIM) in Disease Center - Phase 2.82025
P30CA021765Cancer Center Support Grant (CCSG)72025
R01AG038664Regulation of the Autophagy Pathway with Age and in Long-lived Animals72025
R37AI042999Pattern Recognition Receptors and Autophagy in Mtb Control in AIDS72025
P30AG028740University of Florida Older Americans Independence Center (OAIC)62025

1 to 10 of 1,439Source NIH's project files

See all 1,439 nih grants

Papers3,097

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
CircRNA0857 acts as an miRNA sponge to promote Newcastle disease virus replication via modulating autophagy.J Virol202642657874PubTator, text miningPubMed
CLCuMuV-Induced Autophagy Restricts Viral Accumulation in the MED Cryptic Species of Bemisia tabaci.Insects202642652516PubTator, text miningPubMed
Polyphyllin I Orchestrates Autophagy to Reprogram the Tumour Immune Microenvironment and Abrogate Cisplatin Resistance in Non-Small Cell Lung Cancer.Clin Exp Pharmacol Physiol202642595339PubTator, text miningPubMed
TBK1 puts the brakes on IRGQ-mediated autophagy.Autophagy202642576195PubTator, text miningPubMed
Phenethyl isothiocyanate mediates autophagy via the AMPK/mTOR signal pathway in human glioblastoma multiforme cells.Toxicol Appl Pharmacol202642503352PubTator, text miningPubMed
Divergent Autophagy Pathways in Plasmodium: Mechanisms, Functions, and Therapeutic Potential.Mol Microbiol202642473197PubTator, text miningPubMed
A hybrid machine learning framework with two-step feature selection for identifying key biomarkers and drug targets in monkeypox.Biochem Biophys Rep202642434339PubTator, text miningPubMed
Integrative single-cell profiling and explainable AI identify monocyte-metabolic signatures as diagnostic biomarkers and candidate therapeutic targets in tuberculosis.Arch Microbiol202642329418PubTator, text miningPubMed
Targeting the LY6H-PI3K/AKT autophagy axis suppresses HCC malignancy and reveals a druggable vulnerability.Cell Death Dis202642297773PubTator, text miningPubMed
Investigation of the relationship between autophagy and Warburg effect in osteosarcoma cells: An in vitro study.Cancer Treat Res Commun202642229266PubTator, text miningPubMed

1 to 10 of 3,097

See all 3,097 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/64422

GET https://conductscience.org/api/genes/v1/64422/patents?page=2