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Gene · 6443

SGCB: sarcoglycan beta

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. SGCB: sarcoglycan beta. Genes, record 6443. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6443

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Gene

Symbol
SGCB
HGNC
Name
sarcoglycan beta
HGNC
NCBI Gene ID
6443
NCBI Gene
HGNC ID
HGNC:10806
HGNC
Ensembl
ENSG00000163069
NCBI Gene
Aliases
A3b, LGMD2E, LGMDR4, SGC
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q16585Beta-sarcoglycan3180Ensembl, GeneID, HGNC

Source UniProt

Patents47

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026022658 A2026-02-1246Q16585Espacenet
JP 2026004568 A2026-01-1462652Q16585Espacenet
EP 4650780 A22025-11-1910459Q16585Espacenet
JP 2025170362 A2025-11-182Q16585Espacenet
EP 4641201 A22025-10-2910780Q16585Espacenet
JP 2025139591 A2025-09-262Q16585Espacenet
JP 2025139591 A2025-09-2618Q16585Espacenet
JP 2025529142 A2025-09-043930Q16585Espacenet
US 12371689 B22025-07-293930Q16585Espacenet
JP 2025523953 A2025-07-25145Q16585Espacenet

1 to 10 of 47

See all 47 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants820

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleSGCB papersNewest fiscal year
P30CA016672Cancer Center Support Grant52025
P30CA030199Cancer Center Support Grant (CCSG)42025
R01HL098032Omics, mice and men: Development of precision transfusion medicine32025
R01NS090634Whole body single AAV microgene in canine DMD32025
UL1TR001863Yale Clinical and Translational Science Award32025
P30CA023074University of Arizona Cancer Center - Cancer Center Support Grant22025
P30DK084567Mayo Center for Cell Signaling in Gastroenterology22025
R01AR042423Cytoskeletal Interactions of Dystrophin22025
R01CA247992Targeting ferroptosis in radioresistance in lung cancer: mechanisms and preclinical translation22025
R01CA250025Molecular mechanisms driving mesenchymal colorectal cancer22025

1 to 10 of 820Source NIH's project files

See all 820 nih grants

Papers1,640

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
6-Nitrodopamine as a Novel Mediator of Prostatic Smooth Muscle Function in Mouse and Human.Andrology202642746669PubTator, text miningPubMed
Soluble guanylyl cyclase maturation in cells depends on reduction of the incoming heme by a cysteine in the enzyme's beta subunit.J Biol Chem202642710661PubTator, text miningPubMed
Unraveling the NO-sGC-cGMP pathway in BPD-associated pulmonary hypertension.Am J Physiol Heart Circ Physiol202642709032PubTator, text miningPubMed
Whole-Exome Sequencing in Undiagnosed Muscular Dystrophies: A High Diagnostic Yield and Novel Insights From Iranian Families.Hum Mutat202642553504PubTator, text miningPubMed
The Therapeutic Efficacy of Drugs Targeting the NO-sGC-cGMP Pathway in Treatment of Patients With Chronic Thromboembolic Pulmonary Hypertension: A Systematic Review.Pulm Circ202642516671PubTator, text miningPubMed
Defining Haplosufficiency in Autosomal Recessive Limb-Girdle Muscular Dystrophy Using Molecular Markers in Disease Carriers.Neurol Genet202642453854PubTator, text miningPubMed
Pitfalls of Therapies Targeting the Nitric Oxide Signaling Pathway in Heart Failure With Preserved Ejection Fraction.J Cardiovasc Pharmacol202642331613PubTator, text miningPubMed
Generation of two LGMDR4 patients derived induced pluripotent stem cell line carrying the SGCB frameshift mutation (p.Gly129_Arg130insGlnTer).Stem Cell Res202642225003PubTator, text miningPubMed
Homozygous SGCB splice-site variant causes isolated dilated cardiomyopathy through sarcoglycan complex destabilization in East Asians.J Clin Invest202642222889PubTator, text miningPubMed
MicroRNA-155 at the crossroads of inflammation and vascular dysfunction in essential hypertension.Mol Biol Rep202642216994PubTator, text miningPubMed

1 to 10 of 1,640

See all 1,640 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/6443

GET https://conductscience.org/api/genes/v1/6443/patents?page=2