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SGK1: serum/glucocorticoid regulated kinase 1

1 protein, 50 patents, 0 drugs, 0 trials, 3,407 NIH grants and 4,973 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolSGK1HGNC
Nameserum/glucocorticoid regulated kinase 1HGNC
NCBI Gene ID6446NCBI Gene
HGNC IDHGNC:10810HGNC
EnsemblENSG00000118515NCBI Gene
AliasesSGKNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
O00141Serine/threonine-protein kinase Sgk14314Ensembl, GeneID, HGNCUniProt

Patents 50

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1463245O00141Espacenet
EP 4650780 A22025-11-19937O00141Espacenet
EP 4641201 A22025-10-29659O00141Espacenet
EP 4641202 A22025-10-294398O00141Espacenet
JP 2025517969 A2025-06-12659O00141Espacenet
JP 2025517970 A2025-06-12937O00141Espacenet
KR 1020250017231 A2025-02-044398O00141Espacenet
US 11696924 B22023-07-1129O00141Espacenet
US 11446398 B22022-09-2078240O00141Espacenet
JP 2022524081 A2022-04-27181211O00141Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 3407

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant352,025NIH's project files
P30CA016672Cancer Center Support Grant252,025NIH's project files
R01DK056695SGK Regulation of Epithelial Sodium Transport222,025NIH's project files
P30CA014599Cancer Center Support Grant182,025NIH's project files
P30CA125123Baylor College of Medicine Cancer Center - Cancer Center Support Grant132,025NIH's project files
P01CA120964Molecular Pathogenesis of the Hamartoma Syndromes122,025NIH's project files
P30CA068485Cancer Center Support Grant102,025NIH's project files
P40OD010440Caenorhabditis Genetics Center102,025NIH's project files
R01HL147818ENaC regulation and its role in blood pressure homeostasis102,025NIH's project files
P01AI039671Costimulatory Mechanisms of Autoimmunity82,025NIH's project files

Papers 4973

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42804341PubTator, text miningPubMed
42779791PubTator, text miningPubMed
42758816PubTator, text miningPubMed
42745287PubTator, text miningPubMed
42743771PubTator, text miningPubMed
42737428PubTator, text miningPubMed
42716156PubTator, text miningPubMed
42715516PubTator, text miningPubMed
42695966PubTator, text miningPubMed
42633230PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license