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SHC1: SHC adaptor protein 1

1 protein, 32 patents, 0 drugs, 0 trials, 4,013 NIH grants and 6,470 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolSHC1HGNC
NameSHC adaptor protein 1HGNC
NCBI Gene ID6464NCBI Gene
HGNC IDHGNC:10840HGNC
EnsemblENSG00000160691NCBI Gene
AliasesSHC, SHCA, ShcA, p66NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P29353SHC-transforming protein 158311Ensembl, GeneID, HGNCUniProt

Patents 32

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-198458P29353Espacenet
EP 4641201 A22025-10-298622P29353Espacenet
JP 2025517969 A2025-06-128622P29353Espacenet
JP 2025517970 A2025-06-128458P29353Espacenet
JP 2024123008 A2024-09-108386P29353Espacenet
KR 1020230161313 A2023-11-271P29353Espacenet
JP 2023123507 A2023-09-0591P29353Espacenet
US 11708396 B22023-07-251971P29353Espacenet
US 11446398 B22022-09-2078734P29353Espacenet
JP 2022537339 A2022-08-2586P29353Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 4013

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant492,025NIH's project files
P30CA008748Cancer Center Support Grant362,025NIH's project files
P30CA006927Comprehensive Cancer Center Program at Fox Chase162,025NIH's project files
P30CA076292Moffitt Cancer Center Support Grant152,025NIH's project files
P30DK036836Diabetes Research Center142,025NIH's project files
P30CA046934University of Colorado Cancer Center Support Grant132,025NIH's project files
P30CA014051Cancer Center Support (Core) Grant122,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)122,025NIH's project files
P30CA036727Buffett Cancer Center Support Grant122,025NIH's project files
P30CA016056Roswell Park Cancer Center Support Grant82,025NIH's project files

Papers 6470

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42818064PubTator, text miningPubMed
42793099PubTator, text miningPubMed
42779257PubTator, text miningPubMed
42778663PubTator, text miningPubMed
42764186PubTator, text miningPubMed
42544043PubTator, text miningPubMed
42539625PubTator, text miningPubMed
42528957PubTator, text miningPubMed
42527666PubTator, text miningPubMed
42489559PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license