ConductScience.org, home

Library / Genes

SHH: sonic hedgehog signaling molecule

1 protein, 66 patents, 0 drugs, 0 trials, 9,995 NIH grants and 19,808 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolSHHHGNC
Namesonic hedgehog signaling moleculeHGNC
NCBI Gene ID6469NCBI Gene
HGNC IDHGNC:10848HGNC
EnsemblENSG00000164690NCBI Gene
AliasesHHG1, HLP3, HPE3, MCOPCB5, SMMCI, ShhNC, TPT, TPTPSNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q15465Sonic hedgehog protein46220Ensembl, GeneID, HGNCUniProt

Patents 66

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1464926Q15465Espacenet
EP 4650780 A22025-11-193804Q15465Espacenet
JP 2025147176 A2025-10-0612225Q15465Espacenet
JP 2025529142 A2025-09-047712Q15465Espacenet
JP 2025119783 A2025-08-155Q15465Espacenet
US 12371689 B22025-07-297712Q15465Espacenet
JP 2025517970 A2025-06-123804Q15465Espacenet
JP 2025028160 A2025-02-2812225Q15465Espacenet
KR 1020250010750 A2025-01-2112225Q15465Espacenet
JP 2024109657 A2024-08-1412232Q15465Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 9995

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant1112,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)832,025NIH's project files
P30CA016672Cancer Center Support Grant722,025NIH's project files
R01CA159859Dysregulation of the Core Binding Factor Complex Inhibits Differentiation and Drives Group 4 Medulloblastoma672,025NIH's project files
P01CA096832NORMAL & NEOPLASTIC GROWTH IN THE BRAIN622,025NIH's project files
P30CA046934University of Colorado Cancer Center Support Grant332,025NIH's project files
P30CA006973Regional Oncology Research Center282,025NIH's project files
P30CA030199Cancer Center Support Grant (CCSG)282,025NIH's project files
P30DK084567Mayo Center for Cell Signaling in Gastroenterology262,025NIH's project files
P30CA046592University of Michigan Rogel Cancer Center Support Grant 2023-2028242,025NIH's project files

Papers 19808

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42813612PubTator, text miningPubMed
42812532PubTator, text miningPubMed
42808229PubTator, text miningPubMed
42780569PubTator, text miningPubMed
42774993PubTator, text miningPubMed
42773474PubTator, text miningPubMed
42761752PubTator, text miningPubMed
42758533PubTator, text miningPubMed
42751568PubTator, text miningPubMed
42746039PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license