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SHMT2: serine hydroxymethyltransferase 2
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Gene · 6472

Papers2,556

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

21 to 40 of 2,556

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TitleJournalYearPMIDFound bySource
Epigenetics of Genes Displaying High and Preferential Expression in Myoblasts.Epigenomes202641892369PubTator, text miningPubMed
The oncogenic control of nucleotide synthesis.Oncogenesis202641881963PubTator, text miningPubMed
Novel nitric oxide-releasing triptolidenol derivatives suppress gastric cancer by targeting the folate one-carbon metabolism pathway and inducing ROS accumulation.Eur J Med Chem202641855880PubTator, text miningPubMed
Gene Amplification in Rhabdomyosarcoma: Lessons from a Rare Cancer.Int J Mol Sci202641828638PubTator, text miningPubMed
Mitochondrial uncoupling inhibits serine catabolism via FTO activation in metastatic breast cancer.Cancer Biol Med202641821182PubTator, text miningPubMed
A metabolic-immune subtype of breast cancer defined by G6PD and SHMT2: From single‑cell dissection to dual-targeted therapy.J Steroid Biochem Mol Biol202641819344PubTator, text miningPubMed
SHMT2 inhibition triggers mitochondrial apoptosis to suppress lung adenocarcinoma progression.J Transl Med202641814419PubTator, text miningPubMed
Native chromatome profiling reveals hundreds of metabolic enzymes in the nucleus across tissues.Nat Commun202641792114PubTator, text miningPubMed
Prostate‑specific membrane antigen: Molecular functions and emerging roles as a therapeutic target (Review).Mol Med Rep202641789574PubTator, text miningPubMed
Identification of multigene predictors of prognosis in patients with ovarian cancer.iScience202641767263PubTator, text miningPubMed
RNA-Seq of Gingival Fibroblasts Grown on Collagen Membranes and Hyaluronic Acid.J Funct Biomater202641745519PubTator, text miningPubMed
Metabolic Vulnerabilities as a Therapeutic Target in Breast Cancer.Curr Oncol202641744893PubTator, text miningPubMed
Erastin-induced ferroptosis enhances natural killer cell anti-tumor activity and offers therapeutic potential in neuroblastoma.Front Immunol202641743726PubTator, text miningPubMed
The molecular mechanisms and potential therapeutic implications of the crosstalk between DNA methylation and metabolic reprogramming in thyroid cancer.Cell Death Discov202641741426PubTator, text miningPubMed
Mitochondrial bioenergetics-SASP crosstalk determines senolytic efficacy in therapy-induced senescence.Cell Death Discov202641714592PubTator, text miningPubMed
Metabolic remodeling and immune evasion in glioblastoma: a focus on serine and lipid networks.Front Oncol202641710656PubTator, text miningPubMed
ΔNp63α drives serine synthesis to promote carboplatin resistance in NSCLC.Cell Death Dis202641702885PubTator, text miningPubMed
Comparative transcriptomics analysis of histone deacetylases, transcription factors, and ion channel genes in human iPSC-cardiomyocytes vs. the adult human heart.bioRxiv202641648544PubTator, text miningPubMed
Proximity labeling reveals non-catalytic interactions between DPP9 and ubiquitin signaling complexes.Cell Mol Life Sci202641636814PubTator, text miningPubMed
RNA-Based Therapies for Inherited Metabolic Disorders.J Inherit Metab Dis202641621836PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

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Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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