Gene · 6473
SHOX: SHOX homeobox
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. SHOX: SHOX homeobox. Genes, record 6473. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6473
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| O15266 | Short stature homeobox protein | 292 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents27
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 63453 | O15266 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 63454 | O15266 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 10805 | O15266 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 15608 | O15266 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 10805 | O15266 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 15608 | O15266 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 15608 | O15266 | Espacenet |
| JP 2024109657 A | 2024-08-14 | 15447 | O15266 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 78817 | O15266 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 78818 | O15266 | Espacenet |
1 to 10 of 27
See all 27 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants391
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | SHOX papers | Newest fiscal year |
|---|---|---|---|
| ZIAHD000640 | Regulation Of Childhood Growth | 10 | 2025 |
| R01DK075787 | Biological Insights from Genetic Investigation of ANthropometric Traits (GIANT) Across the Allelic Spectrum | 3 | 2025 |
| P40OD019794 | Ambystoma Genetic Stock Center | 2 | 2025 |
| R01MH074090 | Gene Dosage Imbalance in Neurodevelopmental Disorders | 2 | 2025 |
| T32GM008638 | Medical Genetics Research Training Grant | 2 | 2025 |
| U10AA008401 | Collaborative Study on the Genetics of Alcoholism (COGA). | 2 | 2025 |
| D43TW009114 | Psychiatric research infrastructure for intervention and implementation in India – TEAMS | 1 | 2025 |
| IK6BX004854 | BLRD Research Career Scientist Award Application | 1 | 2025 |
| K12GM093857 | Virginia Commonwealth University IRACDA | 1 | 2025 |
| K12HD052896 | Child Health Research Career Development Award (CHRCDA) Program (K12) | 1 | 2025 |
1 to 10 of 391Source NIH's project files
See all 391 nih grantsPapers1,180
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Idiopathic short stature in the genomic era: a focused narrative review of genotype-phenotype correlation, selective neuroimaging, IGF-1 biology, and growth hormone responsiveness. | Clin Pediatr Endocrinol | 2026 | 42824949 | PubTator, text mining | PubMed |
| Brachydactyly Type A1 Caused by an IHH Variant in a Patient with Disproportionate Short Stature: A Case Report. | Reports (MDPI) | 2026 | 42784019 | PubTator, text mining | PubMed |
| Familial short stature: genetic architecture, risk stratification, and precision management. | Front Endocrinol (Lausanne) | 2026 | 42713069 | PubTator, text mining | PubMed |
Precision medicine in pediatric growth disorders: Integrating clinical phenotype, genetics, IGF-1 biology and artificial intelligence: A systematic scoping review of PubMed-indexed literature (2000-2026). | Growth Horm IGF Res | 2026 | 42628320 | PubTator, text mining | PubMed |
| Langer mesomelic dysplasia as a rare manifestation of SHOX deficiency: a narrative review. | Front Genet | 2026 | 42553923 | PubTator, text mining | PubMed |
| Integrated cardiac, endocrine, and genetic assessment in adolescent basketball players. | Front Endocrinol (Lausanne) | 2026 | 42548527 | PubTator, text mining | PubMed |
| Combined optical genome mapping and cnv-seq identify complex Y-chromosome rearrangements and ectopy in 46,XX testicular disorder of sex development. | Mol Cytogenet | 2026 | 42289734 | PubTator, text mining | PubMed |
| Growth hormone therapy and near-final height in SHOX deficiency and turner syndrome: a real-world single-center retrospective cohort study. | Eur J Pediatr | 2026 | 42243538 | PubTator, text mining | PubMed |
| A qPCR-based algorithm for the diagnosis of classic and non-classic Turner syndrome. | Indian J Med Res | 2026 | 42237825 | PubTator, text mining | PubMed |
| GLI1-fusion neoplasm of the tongue: report of a pediatric case associated with SHOX deficiency disorder. | Virchows Arch | 2026 | 42159714 | PubTator, text mining | PubMed |
1 to 10 of 1,180
See all 1,180 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/6473
GET https://conductscience.org/api/genes/v1/6473/patents?page=2