Gene · 64772
ENGASE: endo-beta-N-acetylglucosaminidase
12 sourcesgene-search-2026-11-11-0.2.0
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ConductScience Library. ENGASE: endo-beta-N-acetylglucosaminidase. Genes, record 64772. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/64772
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Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q8NFI3 | Cytosolic endo-beta-N-acetylglucosaminidase | 743 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents18
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4650780 A2 | 2025-11-19 | 17438 | Q8NFI3 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 17438 | Q8NFI3 | Espacenet |
| US 11564998 B2 | 2023-01-31 | 8973 | Q8NFI3 | Espacenet |
| US 11564998 B2 | 2023-01-31 | 9170 | Q8NFI3 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 27221 | Q8NFI3 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 130192 | Q8NFI3 | Espacenet |
| US 11078247 B2 | 2021-08-03 | 3555 | Q8NFI3 | Espacenet |
| WO 2020043864 A1 | 2020-03-05 | 795 | Q8NFI3 | Espacenet |
| US 10463751 B2 | 2019-11-05 | 8973 | Q8NFI3 | Espacenet |
| US 10463751 B2 | 2019-11-05 | 9170 | Q8NFI3 | Espacenet |
1 to 10 of 18
See all 18 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants731
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | ENGASE papers | Newest fiscal year |
|---|---|---|---|
| R01AI149297 | Engineering IgG-specific endoglycosidases to selectively defeat effector functions | 5 | 2025 |
| P30CA014195 | Cancer Center Support Grant (CCSG) | 4 | 2025 |
| P30CA013330 | Cancer Center Support Grant | 3 | 2025 |
| T32HL007088 | Pre-and Postgraduate Training in Molecular Hematology | 3 | 2025 |
| P30CA014051 | Cancer Center Support (Core) Grant | 2 | 2025 |
| P30CA021765 | Cancer Center Support Grant (CCSG) | 2 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 2 | 2025 |
| P30EY008126 | Core Grant in Vision Research | 2 | 2025 |
| T32AI095190 | Signaling Pathways in Innate Immunity | 2 | 2025 |
| P01HL131474 | Protein Glycosylation in the Coagulopathy and Inflammation of Sepsis | 1 | 2025 |
1 to 10 of 731Source NIH's project files
See all 731 nih grantsPapers1,359
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Circulating cell type senescence signatures track distinct dimensions of health status and trajectories in human longitudinal cohorts. | Cell Rep | 2026 | 42276069 | PubTator, text mining | PubMed |
| Glycan pairing in therapeutic IgG orchestrates Fcγ receptor engagement and ADCC: an integrated structure-function approach for thorough evaluation of Fc N-glycans as critical quality attributes. | MAbs | 2026 | 41925250 | PubTator, text mining | PubMed |
| Site-Specific Glycan Conjugation Improves Stability and Efficacy of an Antibody-Drug Conjugates Bearing DXd as a Cytotoxic Payload. | ACS Omega | 2026 | 41799094 | PubTator, text mining | PubMed |
| Crystal structure of endo-β-N-acetylglucosaminidase HSα. | Acta Crystallogr F Struct Biol Commun | 2026 | 41784007 | PubTator, text mining | PubMed |
| CT Radiogenomics Provides a Novel Factor for cM0(i+) Risk Stratification in Localized Renal Cell Carcinoma: A Model Linked to a Circulating Tumor Cell-Related Gene Signature. | Acad Radiol | 2026 | 41765704 | PubTator, text mining | PubMed |
| Group A Streptococcal Virulence Factors and Vaccine Development-An Update. | Microorganisms | 2026 | 41753644 | PubTator, text mining | PubMed |
| Circulating Cell Type Senescence Signatures Reveal High-Resolution Health Status and Trajectories in Human Longitudinal Studies. | medRxiv | 2026 | 41728302 | PubTator, text mining | PubMed |
| Simultaneous detection of PNGase and ENGase activities in tissue lysate or cytosol using a simply designed high-mannose-type glycopeptide probe containing an Asn-leu-leu sequence. | Bioorg Med Chem Lett | 2026 | 41687896 | PubTator, text mining | PubMed |
| Identification of potential therapeutic targets for stroke and its subtypes by integrating proteomes and genetics from human plasma. | Brain Commun | 2026 | 41488603 | PubTator, text mining | PubMed |
| Deciphering the molecular basis of skin color variation through transcriptomics and machine learning. | Sci Rep | 2025 | 41419520 | PubTator, text mining | PubMed |
1 to 10 of 1,359
See all 1,359 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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