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Gene · 64919

BCL11B: BCL11 transcription factor B

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. BCL11B: BCL11 transcription factor B. Genes, record 64919. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/64919

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Gene

Symbol
BCL11B
HGNC
Name
BCL11 transcription factor B
HGNC
NCBI Gene ID
64919
NCBI Gene
HGNC ID
HGNC:13222
HGNC
Ensembl
ENSG00000127152
NCBI Gene
Aliases
ATL1, ATL1-alpha, ATL1-beta, ATL1-delta, ATL1-gamma, CTIP-2, CTIP2, IDDFSTA, IMD49, RIT1, SMARCM2, ZNF856B, hRIT1-alpha
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9C0K0B-cell lymphoma/leukemia 11B8946Ensembl, GeneID, HGNC

Source UniProt

Patents40

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1438662Q9C0K0Espacenet
JP 2025164846 A2025-10-3042Q9C0K0Espacenet
EP 4641201 A22025-10-297353Q9C0K0Espacenet
JP 2025147176 A2025-10-0614791Q9C0K0Espacenet
JP 2025517969 A2025-06-127353Q9C0K0Espacenet
JP 2025062604 A2025-04-148444Q9C0K0Espacenet
JP 2025032204 A2025-03-1125133Q9C0K0Espacenet
JP 2025032204 A2025-03-1125136Q9C0K0Espacenet
JP 2025028160 A2025-02-2814791Q9C0K0Espacenet
KR 1020250010750 A2025-01-2114791Q9C0K0Espacenet

1 to 10 of 40

See all 40 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,751

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleBCL11B papersNewest fiscal year
P30CA008748Cancer Center Support Grant202025
P30CA021765Cancer Center Support Grant (CCSG)152025
UL1TR001863Yale Clinical and Translational Science Award122025
R35CA197695Translating genomic discoveries to improved outcomes for high risk acute leukemia92025
U10CA180886COG NCTN Network Group Operations Center - Year 11 STAR Act MCI and PEC Supplement82025
P30CA016058Cancer Center Support Grant72025
R01MH113257Yale Macaque Brain Resource72025
R35NS116843Continuous Neurogenesis in the Mammalian Hippocampus72025
U10CA180899Children's Oncology Group Statistics and Data Center72025
P30AI027763UCSF-Bay Area Center for AIDS Research62025

1 to 10 of 2,751Source NIH's project files

See all 2,751 nih grants

Papers2,697

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
BCL11B predetermines a persister state in breast cancer that is reversed by TNFα.Sci Adv202642715302PubTator, text miningPubMed
ALA-PDT for giant condyloma acuminatum in an immunodeficient child with BCL11B mutation: safety and efficacy.Photodiagnosis Photodyn Ther202642674263PubTator, text miningPubMed
Benzo[a]pyrene-induced AHR activation in human ESCs primes premature neurogenesis in cerebral organoids.J Hazard Mater202642667716PubTator, text miningPubMed
BCL11B targeting in tumor CD8 + T cells amplifies anti-tumor response by blocking exhaustion while promoting stemness and cytotoxicity.bioRxiv202642601873PubTator, text miningPubMed
The Bcl11-Cxxc1 axis regulates stage-specific chromatin accessibility during lymphocyte development.Genes Dev202642547288PubTator, text miningPubMed
Bcl11b dose-dependently regulates positive selection of CD8 T cells to the virtual memory fate.bioRxiv202642465258PubTator, text miningPubMed
RNA-binding protein RALYL-mediated BCL11B RNA stability promotes immune escape in small cell lung cancer through transcriptional activation of BUB3.Cell Oncol (Dordr)202642455237PubTator, text miningPubMed
miR-132 overexpression is associated with modulation in miR-21 expression and glioblastoma cell behavior.PLoS One202642430385PubTator, text miningPubMed
iPSC Neurodegenerative Disease Initiative isogenic CAG repeat iPSC line for Huntington's disease.bioRxiv202642427629PubTator, text miningPubMed
Palmitic acid-induced metabolic stress alters differentiation-associated gene expression in human ameloblast-like cells.Biochem Biophys Res Commun202642398335PubTator, text miningPubMed

1 to 10 of 2,697

See all 2,697 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/64919

GET https://conductscience.org/api/genes/v1/64919/patents?page=2