Gene · 6497
SKI: SKI proto-oncogene
12 sourcesgene-search-2026-11-11-0.2.0
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ConductScience Library. SKI: SKI proto-oncogene. Genes, record 6497. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6497
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Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P12755 | Ski oncogene | 728 | 4 | Ensembl, GeneID, HGNC |
Source UniProt
Patents20
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 69768 | P12755 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 10052 | P12755 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 15618 | P12755 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 10052 | P12755 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 15618 | P12755 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 15618 | P12755 | Espacenet |
| JP 2024109657 A | 2024-08-14 | 15457 | P12755 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 79495 | P12755 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 182466 | P12755 | Espacenet |
| JP 2021536249 A | 2021-12-27 | 15811 | P12755 | Espacenet |
1 to 10 of 20
See all 20 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,067
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | SKI papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 8 | 2025 |
| UL1TR001863 | Yale Clinical and Translational Science Award | 6 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 4 | 2025 |
| P30CA030199 | Cancer Center Support Grant (CCSG) | 4 | 2025 |
| P30CA047904 | Cancer Center Support Grant | 3 | 2025 |
| R01AI123193 | Functional protein networks underlying T cell growth, proliferation and differentiation | 3 | 2025 |
| R01EY012200 | Pax6 as a key regulator of lens development | 3 | 2025 |
| R35GM118080 | Structural studies of RNA processing and ubiquitin-like protein modification | 3 | 2025 |
| K08HL159346 | Deep learning to enable the genetic analysis of aorta | 2 | 2025 |
| P01CA163222 | Targetable epigenetic and transcriptional mechanisms in melanoma thatshape the microenvironment | 2 | 2025 |
1 to 10 of 1,067Source NIH's project files
See all 1,067 nih grantsPapers1,424
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| A transcription factor-focused CRISPR screen identifies SKI as a BCL11A-independent repressor of ζ-globin. | J Genet Genomics | 2026 | 42710656 | PubTator, text mining | PubMed |
| SKI is critical to counter TGF-β signaling to promote T cell function and autoimmunity. | Sci Adv | 2026 | 42616872 | PubTator, text mining | PubMed |
| SnoN Is Involved in Regulation of the TGFβ/Smad Signaling Pathway in Patients with Degenerative Lumbar Canal Stenosis. | Neurol Med Chir (Tokyo) | 2026 | 42572278 | PubTator, text mining | PubMed |
| Genome-wide assessment of rare protein-coding variants identifies associations with non-syndromic cleft lip/palate. | Eur J Hum Genet | 2026 | 42477406 | PubTator, text mining | PubMed |
| A Combination of Variants in SEPTIN9 and MSX1 Genes Leads to the Formation of Orofacial Clefts. | Genes Cells | 2026 | 42429105 | PubTator, text mining | PubMed |
| Evidence-based classification of genes implicated in craniosynostosis disorders using the ClinGen curation framework. | Genet Med | 2026 | 42059179 | PubTator, text mining | PubMed |
| Proteasome dysfunction underlies HERC2-linked neurodevelopmental disorder with Angelman-like clinical features. | Cell Death Discov | 2026 | 41951624 | PubTator, text mining | PubMed |
| Differential MicroRNA Expression in Chronic Spontaneous Urticaria in Relation to Treatment Response. | Allergy Asthma Immunol Res | 2026 | 41914533 | PubTator, text mining | PubMed |
| Chromatin accessibility regulates age-dependent nuclear mechanotransduction. | Proc Natl Acad Sci U S A | 2026 | 41886372 | PubTator, text mining | PubMed |
| Shenkang Injection Prevents Contrast-Induced Nephropathy by Regulating Ferroptosis Via the STAT3/HIF-1α/HMOX-1 Pathways. | Comb Chem High Throughput Screen | 2026 | 41830078 | PubTator, text mining | PubMed |
1 to 10 of 1,424
See all 1,424 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/6497
GET https://conductscience.org/api/genes/v1/6497/patents