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Gene · 6505

SLC1A1: solute carrier family 1 member 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. SLC1A1: solute carrier family 1 member 1. Genes, record 6505. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6505

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Gene

Symbol
SLC1A1
HGNC
Name
solute carrier family 1 member 1
HGNC
NCBI Gene ID
6505
NCBI Gene
HGNC ID
HGNC:10939
HGNC
Ensembl
ENSG00000106688
NCBI Gene
Aliases
DCBXA, EAAC1, EAAT3, SCZD18, hEAAC1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P43005Excitatory amino acid transporter 352423Ensembl, GeneID, HGNC

Source UniProt

Patents24

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
WO 2026079407 A2026-04-1689P43005Espacenet
JP 2026004568 A2026-01-1463950P43005Espacenet
EP 4650780 A22025-11-192055P43005Espacenet
JP 2025529142 A2025-09-044039P43005Espacenet
US 12371689 B22025-07-294039P43005Espacenet
JP 2025517970 A2025-06-122055P43005Espacenet
JP 2025032204 A2025-03-1135804P43005Espacenet
EP 4516316 A12025-03-0589P43005Espacenet
EP 4461818 A22024-11-1335804P43005Espacenet
WO 2023210585 A2023-11-0289P43005Espacenet

1 to 10 of 24

See all 24 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,348

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleSLC1A1 papersNewest fiscal year
ZIAMH002946Structure, Function and Pharmacology of Neurotransmitter Reuptake Systems82025
R01MH059299Multimodal Investigation of Excitatory/Inhibitory Imbalances and Network Dysfunction Related to Motor Control in OCD Youth: ¹H fMRS and fMRI Applications62025
R25MH077823Research Education for Future Physician-Scientists in Child Psychiatry52025
P30CA068485Cancer Center Support Grant42025
P50HD103525WASHINGTON UNIVERSITY INTELLECTUAL AND DEVELOPMENTAL DISABILITIES RESEARCH CENTER42025
R01ES010563Mechanisms of Manganese Neurotoxicity42025
ZIAMH002857Glutamatergic Modulators for Rapid and Sustained Antidepressant Effect42025
P30CA014236Cancer Center Support Grant (CCSG)32025
P30EY008126Core Grant in Vision Research32025
U10AA008401Collaborative Study on the Genetics of Alcoholism (COGA).32025

1 to 10 of 1,348Source NIH's project files

See all 1,348 nih grants

Papers1,977

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
A coupled iron-hypoxia selection model for the evolution of endometriosis-associated ovarian clear cell carcinoma.Front Oncol202642819154PubTator, text miningPubMed
Glutathione in brain oxidative stress: from redox chemistry to clinical imaging.Arch Toxicol202642816634PubTator, text miningPubMed
Multifaceted In Silico and DFT-Based Analysis of 2‑Aminosuccinic Acid on Ferroptosis-Related Targets.ACS Omega202642799062PubTator, text miningPubMed
Drinking Slightly Acidic Electrolyzed Water Promotes Growth Performance, Improves Digestion, and Modulates Antioxidant Status in Weaned Piglets.Animals (Basel)202642511002PubTator, text miningPubMed
Redox-dependent mitochondrial dynamics: PLK1 couples glutathione metabolism to ROS-driven JNK and DUSP6 pathways in colorectal cancer.Free Radic Biol Med202642448060PubTator, text miningPubMed
Targeting of solute carrier family 1 member 1 that links metabolic reprogramming and ferroptosis sensitivity in pancreatic ductal adenocarcinoma.Oncogene202642432328PubTator, text miningPubMed
Immune and clinicopathological features of molecularly defined prolactinoma subtypes.J Neurosurg202642361377PubTator, text miningPubMed
Transcriptomic Profile of Genes Regulating Cellular Response to Extra- and Intracellular Stimuli in Porcine Ovarian Granulosa Cells During In Vitro Cultivation.Int J Mol Sci202642353161PubTator, text miningPubMed
Cation homeostasis-related prognostic genes uncovered by transcriptomic analysis in breast cancer.Transl Cancer Res202642305482PubTator, text miningPubMed
Clozapine and obsessive-compulsive symptoms: Integrating clinical outcomes, mechanisms, and precision psychiatry approaches.Prog Neuropsychopharmacol Biol Psychiatry202642285472PubTator, text miningPubMed

1 to 10 of 1,977

See all 1,977 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/6505

GET https://conductscience.org/api/genes/v1/6505/patents?page=2