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Gene · 65057

ACD: ACD shelterin complex subunit and telomerase recruitment factor

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ACD: ACD shelterin complex subunit and telomerase recruitment factor. Genes, record 65057. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/65057

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Gene

Symbol
ACD
HGNC
Name
ACD shelterin complex subunit and telomerase recruitment factor
HGNC
NCBI Gene ID
65057
NCBI Gene
HGNC ID
HGNC:25070
HGNC
Ensembl
ENSG00000102977
NCBI Gene
Aliases
DKCA6, DKCB7, PIP1, PTOP, Pip1, Ptop, TINT1, TPP1, Tint1, Tpp1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q96AP0Adrenocortical dysplasia protein homolog45828Ensembl, GeneID, HGNC

Source UniProt

Patents5

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-1918301Q96AP0Espacenet
JP 2025517970 A2025-06-1218301Q96AP0Espacenet
JP 2025062604 A2025-04-143480Q96AP0Espacenet
US 11446398 B22022-09-203480Q96AP0Espacenet
JP 2022524081 A2022-04-27106451Q96AP0Espacenet

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,129

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleACD papersNewest fiscal year
ZIACP010190Genetic Epidemiology of Telomere Maintenance and Cancer Etiology162025
P30CA008748Cancer Center Support Grant92025
P30CA046592University of Michigan Rogel Cancer Center Support Grant 2023-202882025
R01DK062027Mechanisms of Adrenal Differentiation82025
ZIACP010144Clinical Genetic Studies of Familial and Hereditary Cancer Syndromes62025
P30CA016672Cancer Center Support Grant52025
P30CA125123Baylor College of Medicine Cancer Center - Cancer Center Support Grant52025
ZIACP004410Family Studies52025
P30CA010815Consolidated Basic Cancer Research Program42025
R01AG016642Mechanism of the telomeric proliferation limit42025

1 to 10 of 1,129Source NIH's project files

See all 1,129 nih grants

Papers1,628

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Agreement between Sirius Scheimpflug-Placido tomography and Anterion swept-source OCT in keratoconic eyes stratified by prior corneal cross-linking: a retrospective cross-sectional agreement study.Int Ophthalmol202642726338PubTator, text miningPubMed
Cyclodextrin-Modulated Electrochemical Grafting of Graphite Surfaces with Aryldiazonium Salts.Langmuir202642709080PubTator, text miningPubMed
Encapsulation of Polyhedral Borane Cluster trans-[B20H18]2- in Cyclodextrins: Stabilizing Effect in Aqueous Solution.Inorg Chem202642704196PubTator, text miningPubMed
Inclusion Complexation of Native and Functionalized α-, β-, and γ-Cyclodextrins with PFAS: An Experimental and Molecular Simulation Study.J Phys Chem B202642470374PubTator, text miningPubMed
The Role of Genetics in Malignant Melanoma: A Comprehensive Review.Surg Clin North Am202642419313PubTator, text miningPubMed
Telomere maintaining germline and somatic variants in thyroid cancer and melanoma.medRxiv202642245030PubTator, text miningPubMed
Prevalence of Familial Melanoma Genes and Cancer Risk Among Genomically Ascertained Individuals.JAMA Dermatol202642201696PubTator, text miningPubMed
The regulation of mitochondrial ferritin on mitochondrial redox balance is essential to cell fate decision.Redox Biol202641844496PubTator, text miningPubMed
Whole exome sequencing identified two novel mutations of ACD in Chinese patients with idiopathic pulmonary fibrosis.Front Cell Dev Biol202641822348PubTator, text miningPubMed
Dyskeratosis Congenita: Clinical Phenotype and Genetic Features in a Sibling Pair.Clin Cosmet Investig Dermatol202641809525PubTator, text miningPubMed

1 to 10 of 1,628

See all 1,628 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/65057

GET https://conductscience.org/api/genes/v1/65057/grants?page=2