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Gene · 65078

RTN4R: reticulon 4 receptor

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. RTN4R: reticulon 4 receptor. Genes, record 65078. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/65078

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Gene

Symbol
RTN4R
HGNC
Name
reticulon 4 receptor
HGNC
NCBI Gene ID
65078
NCBI Gene
HGNC ID
HGNC:18601
HGNC
Ensembl
ENSG00000040608
NCBI Gene
Aliases
NGR, NOGOR, NgR, NgR1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9BZR6Reticulon-4 receptor4732Ensembl, GeneID, HGNC

Source UniProt

Patents383

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4705273 A22026-03-11369Q9BZR6Espacenet
JP 2026004568 A2026-01-1461450Q9BZR6Espacenet
EP 4650780 A22025-11-1976Q9BZR6Espacenet
JP 2025529142 A2025-09-043794Q9BZR6Espacenet
US 12371689 B22025-07-293794Q9BZR6Espacenet
JP 2025517970 A2025-06-1276Q9BZR6Espacenet
JP 2025032204 A2025-03-1135096Q9BZR6Espacenet
JP 2025013347 A2025-01-24369Q9BZR6Espacenet
EP 4461818 A22024-11-1335096Q9BZR6Espacenet
EP 4406585 A22024-07-31369Q9BZR6Espacenet

1 to 10 of 383

See all 383 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants834

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleRTN4R papersNewest fiscal year
UL1TR001863Yale Clinical and Translational Science Award52025
P30CA014089University of Southern California Norris Comprehensive Cancer Center Support Grant (CCSG)32025
P30CA030199Cancer Center Support Grant (CCSG)32025
R01AG034924mGluR5 and Phase State Dependent Synaptic Loss in Alzheimer's Disease32025
P01CA163227Androgen Receptor Action in Castration Resistant Prostate Cancer22025
P01HL154811Cell Adhesion and Signaling in Blood and Vascular Cells22025
P30CA010815Consolidated Basic Cancer Research Program22025
P30CA016672Cancer Center Support Grant22025
P30CA054174Mays Cancer Center at UT Health SA22025
P30CA068485Cancer Center Support Grant22025

1 to 10 of 834Source NIH's project files

See all 834 nih grants

Papers1,314

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Circulating proteins as key genetically proxied mediators in the pathway from smoking to intracranial aneurysm disease: A mediation Mendelian randomization analysis.Tob Induc Dis202642774843PubTator, text miningPubMed
Plasma Proteomic Profiles Predict Subsequent Obstructive Sleep Apnea Diagnosis in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease.FASEB J202642561003PubTator, text miningPubMed
Analytical and clinical validation of a novel proximity extension assay-based plasma biomarker panel in a cohort of prevalent neurodegenerative dementias.Alzheimers Res Ther202642436533PubTator, text miningPubMed
From Molecules to Biomarkers: Nogo Proteins and Receptors in the Early Detection of Type 2 Diabetes Complications: A Systematic Review.Int J Mol Sci202642278646PubTator, text miningPubMed
Retraction notice to "HBO suppresses Nogo-A, Ng-R, or RhoA expression in the cerebral cortex after global ischemia" [Biochem. Biophys. Res. Commun. 309 (2003) 368-376].Biochem Biophys Res Commun202642020290PubTator, text miningPubMed
Identification of suicide brain transcriptomic signatures using meta-analysis of multiple cohorts.Transl Psychiatry202641916959PubTator, text miningPubMed
The Molecular Neurobiology of NG2-Expressing Glial Cells in Cerebral Small Vessel Disease Pathogenesis.Mol Neurobiol202641801572PubTator, text miningPubMed
Deciphering the disease ecosystem of ischemic stroke via multi-omics and prospects for therapeutic strategies.Front Neurosci202641782920PubTator, text miningPubMed
Ischemia-Induced Neurodegeneration in Glaucoma: Mechanistic Insights and Translational Opportunities for Psychoplastogen-Based Therapies.Pharmaceuticals (Basel)202641754856PubTator, text miningPubMed
Identification and validation of paraptosis-related prognostic biomarkers in lung adenocarcinoma: An observational study based on transcriptomics and clinical outcomes.Medicine (Baltimore)202641731832PubTator, text miningPubMed

1 to 10 of 1,314

See all 1,314 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/65078

GET https://conductscience.org/api/genes/v1/65078/patents?page=2