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Gene · 6510

SLC1A5: solute carrier family 1 member 5

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. SLC1A5: solute carrier family 1 member 5. Genes, record 6510. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6510

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Gene

Symbol
SLC1A5
HGNC
Name
solute carrier family 1 member 5
HGNC
NCBI Gene ID
6510
NCBI Gene
HGNC ID
HGNC:10943
HGNC
Ensembl
ENSG00000105281
NCBI Gene
Aliases
AAAT, ASCT2, ATBO, M7V1, M7VS1, R16, RDRC
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q15758Neutral amino acid transporter B(0)54127Ensembl, GeneID, HGNC

Source UniProt

Patents99

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
WO 2026134203 A2026-06-253Q15758Espacenet
JP 2026004568 A2026-01-1463955Q15758Espacenet
EP 4650780 A22025-11-1916330Q15758Espacenet
EP 4641201 A22025-10-2920015Q15758Espacenet
EP 4641202 A22025-10-291129Q15758Espacenet
JP 2025147176 A2025-10-0616547Q15758Espacenet
JP 2025529142 A2025-09-044043Q15758Espacenet
US 12371689 B22025-07-294043Q15758Espacenet
JP 2025517969 A2025-06-1220015Q15758Espacenet
JP 2025517970 A2025-06-1216330Q15758Espacenet

1 to 10 of 99

See all 99 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,927

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleSLC1A5 papersNewest fiscal year
P30CA016672Cancer Center Support Grant282025
P30CA008748Cancer Center Support Grant252025
R01DK105550Exploiting metabolic vulnerabilities of CD4 T cell subsets to control inflammatory disease92025
P30DK058404Molecular and Cellular Basis for Digestive Diseases82025
P30CA068485Cancer Center Support Grant72025
R01ES010563Mechanisms of Manganese Neurotoxicity72025
P30CA021765Cancer Center Support Grant (CCSG)62025
R01CA051497Defining the Role of the Cancer Circadian Clock in Tumor Immunity and Tumorigenesis62025
P30CA016087Cancer Center Support Grant52025
P30CA030199Cancer Center Support Grant (CCSG)52025

1 to 10 of 1,927Source NIH's project files

See all 1,927 nih grants

Papers3,624

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Digital Quantification of Membrane DAB Immunohistochemical Staining in FFPE Cervical Cancer Tissues Using an Open-Source CellProfiler Pipeline.Bio Protoc202642780749PubTator, text miningPubMed
Metabolic profiling of CAR T-cells in patients reveals a shift toward amino acid-supported OXPHOS and informs transporter engineering.Res Sq202642780275PubTator, text miningPubMed
Plasma Feeding Protects the Blood-Brain Barrier Post-Asphyxia While the Blood-CSF Barrier Remains Spared.Stroke202642751786PubTator, text miningPubMed
Amino acid transporters in hepatocellular carcinoma: Gatekeepers of metabolic reprogramming.Mol Biol Rep202642747623PubTator, text miningPubMed
Plumbagin Is a PKM2 Activator That Modulates Glutamine Metabolism and Dependency in Leukemia.Metabolites202642646313PubTator, text miningPubMed
MICAL2 as a key effector of β-catenin signaling driving melanoma progression and therapeutic resistance.Cell Death Differ202642601381PubTator, text miningPubMed
Single-cell and functional profiling identifies an IL6-centered immunometabolic communication circuit in multiple myeloma.Front Immunol202642577287PubTator, text miningPubMed
Human M1 macrophages secrete glutamine: a role for the transporters ASCT2 and SNAT5.Am J Physiol Cell Physiol202642575884PubTator, text miningPubMed
METTL7A Downregulation Drives SLC1A5-Mediated Glutamine Competition to Promote Tumor Proliferation and Suppress CD8+ T Cell Immunity in Gastric Cancer.Adv Sci (Weinh)202642544900PubTator, text miningPubMed
PLK1-mediated phosphorylation of PHGDH reprograms serine metabolism in advanced prostate cancer.Proc Natl Acad Sci U S A202642507939PubTator, text miningPubMed

1 to 10 of 3,624

See all 3,624 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/6510

GET https://conductscience.org/api/genes/v1/6510/patents?page=2