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WNK1: WNK lysine deficient protein kinase 1
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Gene · 65125

Papers2,081

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

1 to 20 of 2,081

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TitleJournalYearPMIDFound bySource
WNK1 Phosphorylation Sites in TBC1D1 and TBC1D4 Modulate Cell-Surface Abundance of GLUT1.Cells202642738876PubTator, text miningPubMed
[225Ac]Ac-iPSMA Radiopharmaceuticals for Targeted Alpha Therapy: Design, Synthesis, and Preclinical Evaluation.Int J Mol Sci202642737682PubTator, text miningPubMed
WNK1: an atypical kinase vulnerability in T-ALL.Blood202642720175PubTator, text miningPubMed
Hypotonicity-Induced WNK1 Phosphorylation Prevents H2O2-Induced Apoptosis in Vascular Smooth Muscle Cells.Basic Clin Pharmacol Toxicol202642675813PubTator, text miningPubMed
WNK-dependent phosphorylation of gephyrin tunes GABAA receptors at inhibitory synapses and modulates anxiety behavior.Proc Natl Acad Sci U S A202642640800PubTator, text miningPubMed
With no lysine kinase 1 in hepatic stellate cells promotes mouse and human liver fibrosis through glycolytic triosephosphate isomerase 1.Hepatology202642560363PubTator, text miningPubMed
miR-337-5p Targets WNK1 to Promote IL-13-Induced Nasal Epithelial Inflammation in Allergic Rhinitis.Int Arch Allergy Immunol202642545909PubTator, text miningPubMed
Genetic Variants in the MTHFR and WNK1 Genes and Their Contribution to Hypertension Susceptibility.Int J Med Sci202642524532PubTator, text miningPubMed
WNK1 is a central osmolality sensor that regulates arginine vasopressin secretion.Curr Opin Nephrol Hypertens202642471779PubTator, text miningPubMed
Discoidin domain receptor 1 contributes to colorectal cancer progression by promoting cell migration and invasion.Life Sci202642462480PubTator, text miningPubMed
Forging New Pathways in Oncology: Strategic Insights from the 17th Annual Frontiers in Cancer Science Conference.Cancer Res202642388021PubTator, text miningPubMed
Targeting WNK1 suppresses acute myeloid leukemia progression and enhances sensitivity to venetoclax.Front Oncol202642326325PubTator, text miningPubMed
Structural Basis for Potassium Inhibition of WNK Kinases.Biochemistry202642186973PubTator, text miningPubMed
Histone H3K27 demethylation drives Crohn's disease inflammation: GSK-J4 as a potential epigenetic therapy.Clin Epigenetics202642169165PubTator, text miningPubMed
Inhibition of the atypical kinase WNK1 as a therapeutic strategy in TAL-related T-cell acute lymphoblastic leukemia.Blood202642154791PubTator, text miningPubMed
Targeting WNK1 Releases Differentiation Block in Acute Myeloid Leukemia.bioRxiv202642079092PubTator, text miningPubMed
Clinical and molecular characteristics of a series of Chinese children with pseudohypoaldosteronism: a case series.Transl Pediatr202641982973PubTator, text miningPubMed
PHGDH phosphorylation mediated by WNK1 serves as a dual marker of metabolic vulnerability and responsiveness to oxaliplatin treatment.Proc Natl Acad Sci U S A202641880577PubTator, text miningPubMed
Bilirubin as a Modulator of WNK1 Protein Signaling: Implications for Neuroinflammatory Diseases.Adv Sci (Weinh)202641861098PubTator, text miningPubMed
Mechanisms underlying the role of TNF-α and IL-1β preconditioned exosomes derived from human umbilical cord mesenchymal stem cells in wound healing.Front Immunol202641782856PubTator, text miningPubMed

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Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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