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Gene · 6518

SLC2A5: solute carrier family 2 member 5

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. SLC2A5: solute carrier family 2 member 5. Genes, record 6518. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6518

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Gene

Symbol
SLC2A5
HGNC
Name
solute carrier family 2 member 5
HGNC
NCBI Gene ID
6518
NCBI Gene
HGNC ID
HGNC:11010
HGNC
Ensembl
ENSG00000142583
NCBI Gene
Aliases
GLUT-5, GLUT5
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P22732Solute carrier family 2, facilitated glucose transporter member 55010Ensembl, GeneID, HGNC

Source UniProt

Patents47

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1464151P22732Espacenet
EP 4650780 A22025-11-199917P22732Espacenet
EP 4641201 A22025-10-2910188P22732Espacenet
JP 2025147176 A2025-10-0612358P22732Espacenet
JP 2025529142 A2025-09-044143P22732Espacenet
JP 2025529142 A2025-09-047730P22732Espacenet
US 12371689 B22025-07-294143P22732Espacenet
US 12371689 B22025-07-297730P22732Espacenet
JP 2025517969 A2025-06-1210188P22732Espacenet
JP 2025517970 A2025-06-129917P22732Espacenet

1 to 10 of 47

See all 47 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants933

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleSLC2A5 papersNewest fiscal year
P30CA008748Cancer Center Support Grant92025
P30CA016672Cancer Center Support Grant62025
P30DK056338Texas Medical Center Digestive Diseases Center52025
R35CA197588Role of Phosphoinositides and Protein Kinases in the control of Cancer Metabolism52025
P30DK042086Center for Interdisciplinary Study of Inflammatory Intestinal DIsorders (C-IID)42025
P30DK048520Colorado Nutrition Obesity Research Center42025
P30DK056341Washington University Nutrition Obesity Research Center42025
ZIABC010830Mechanisms of non-classical multidrug resistance in cancer42025
P30DK020579Diabetes Research Center32025
P30DK034854Integrated Epithelial and Muscosal Biology32025

1 to 10 of 933Source NIH's project files

See all 933 nih grants

Papers1,573

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
GLUT5-Mediated Disruption of the Gut-Testis Axis Deteriorates Olanzapine-Induced Testicular Fibrosis and is Ameliorated by Dapagliflozin.Drug Des Devel Ther202642787161PubTator, text miningPubMed
Fructose induces PERK-dependent ER stress and mitochondrial dysfunction via nucleotide depletion in clear cell renal cell carcinoma.Cell Death Dis202642675041PubTator, text miningPubMed
Microbiota-Neuroinflammation Crosstalk in Primary Brain Tumors: Focus on Glioblastoma.Brain Behav202642553012PubTator, text miningPubMed
The brain's sweet spot: why microglia can run on fructose metabolism.Front Immunol202642519336PubTator, text miningPubMed
Single-Cell Profiling Identifies SLC2A5-Mediated Fructose Metabolism as a Vulnerability in Primary CNS Lymphoma.Adv Sci (Weinh)202642360090PubTator, text miningPubMed
β-Hydroxybutyrate Improves Glucose Metabolism in Streptozotocin-Induced Type 1 Diabetes by Inhibiting Gut and Liver Glucose Transporters via GPR109A.Diabetes202642330303PubTator, text miningPubMed
Differential expression patterns of selective energy metabolism associated genes in fresh and freeze-thawed bubaline spermatozoa at uniform durations of in vitro capacitation.Cryobiology202642308645PubTator, text miningPubMed
Fructose-Based Single-Chain Polymer Nanoparticles for GLUT1-Mediated Delivery: Impact of Polymer Design on Uptake and In Vivo Performance.Adv Healthc Mater202642277625PubTator, text miningPubMed
High-dimensional Spatial Immune Profiling Highlights Microglia-Like Cells in Human Dorsal Root Ganglia.Eur J Immunol202642153599PubTator, text miningPubMed
Fructose metabolism as an adaptive survival axis in pancreatic cancer: mechanistic insights and therapeutic implications.Front Med (Lausanne)202642089053PubTator, text miningPubMed

1 to 10 of 1,573

See all 1,573 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/6518

GET https://conductscience.org/api/genes/v1/6518/patents?page=2