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BMP4: bone morphogenetic protein 4

1 protein, 284 patents, 0 drugs, 0 trials, 8,065 NIH grants and 14,198 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolBMP4HGNC
Namebone morphogenetic protein 4HGNC
NCBI Gene ID652NCBI Gene
HGNC IDHGNC:1071HGNC
EnsemblENSG00000125378NCBI Gene
AliasesBMP2B, BMP2B1, MCOPS6, OFC11, ZYMENCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P12644Bone morphogenetic protein 44080Ensembl, GeneID, HGNCUniProt

Patents 284

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4705273 A22026-03-11171P12644Espacenet
EP 4705273 A22026-03-11172P12644Espacenet
JP 2026004568 A2026-01-1439067P12644Espacenet
JP 2026004568 A2026-01-1439068P12644Espacenet
JP 2026004568 A2026-01-1439069P12644Espacenet
JP 2026004568 A2026-01-1439070P12644Espacenet
EP 4650780 A22025-11-191153P12644Espacenet
WO 2025219552 A12025-10-231P12644Espacenet
JP 2025147176 A2025-10-061497P12644Espacenet
JP 2025147176 A2025-10-061498P12644Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 8065

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant562,025NIH's project files
P30CA016672Cancer Center Support Grant382,025NIH's project files
P30DK078392Digestive Health Center (DHC): Bench to Bedside Research in Pediatric Digestive Disease222,025NIH's project files
P30CA068485Cancer Center Support Grant212,025NIH's project files
R01HL076485Engineering Vascularized Cardiac Muscle212,025NIH's project files
R24HD000836Laboratory of Developmental Biology192,025NIH's project files
P30DK058404Molecular and Cellular Basis for Digestive Diseases182,025NIH's project files
P30CA015704Cancer Center Support Grant162,025NIH's project files
P30CA006973Regional Oncology Research Center142,025NIH's project files
R01HL081397Mechanism of Matrix Gla Protein (MGP); Adipose Fibrosis142,025NIH's project files

Papers 14198

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42818713PubTator, text miningPubMed
42782746PubTator, text miningPubMed
42780575PubTator, text miningPubMed
42771993PubTator, text miningPubMed
42733085PubTator, text miningPubMed
42726637PubTator, text miningPubMed
42712902PubTator, text miningPubMed
42689320PubTator, text miningPubMed
42688129PubTator, text miningPubMed
42675788PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license