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SLC5A2: solute carrier family 5 member 2

1 protein, 37 patents, 19 drugs, 954 trials, 2,530 NIH grants and 16,493 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolSLC5A2HGNC
Namesolute carrier family 5 member 2HGNC
NCBI Gene ID6524NCBI Gene
HGNC IDHGNC:11037HGNC
EnsemblENSG00000140675NCBI Gene
AliasesSGLT2NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P31639Sodium/glucose cotransporter 267212Ensembl, GeneID, HGNCUniProt

Patents 37

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026513237 A2026-04-2338P31639Espacenet
JP 2026004568 A2026-01-1464743P31639Espacenet
EP 4640849 A22025-10-29831P31639Espacenet
EP 4641201 A22025-10-295407P31639Espacenet
JP 2025529142 A2025-09-044269P31639Espacenet
US 12371689 B22025-07-294269P31639Espacenet
JP 2025519096 A2025-06-24831P31639Espacenet
JP 2025517969 A2025-06-125407P31639Espacenet
KR 1020250080786 A2025-06-051P31639Espacenet
WO 2024258820 A22024-12-19358P31639Espacenet

Drugs 19

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
BEXAGLIFLOZINCHEMBL1808388Sodium/glucose cotransporter 2 inhibitorINHIBITORChEMBL
CANAGLIFLOZINCHEMBL4594217Sodium/glucose cotransporter 2 inhibitorINHIBITORChEMBL
CANAGLIFLOZIN ANHYDROUSCHEMBL2048484Sodium/glucose cotransporter 2 inhibitorINHIBITORChEMBL
DAPAGLIFLOZINCHEMBL429910Sodium/glucose cotransporter 2 inhibitorINHIBITORChEMBL
DAPAGLIFLOZIN PROPANEDIOLCHEMBL2103802Sodium/glucose cotransporter 2 inhibitorINHIBITORChEMBL
EMPAGLIFLOZINCHEMBL2107830Sodium/glucose cotransporter 2 inhibitorINHIBITORChEMBL
ERTUGLIFLOZINCHEMBL1770248Sodium/glucose cotransporter 2 inhibitorINHIBITORChEMBL
ERTUGLIFLOZIN PIDOLATECHEMBL5315054Sodium/glucose cotransporter 2 inhibitorINHIBITORChEMBL
HENAGLIFLOZINCHEMBL4297431Sodium/glucose cotransporter 2 inhibitorINHIBITORChEMBL
IPRAGLIFLOZINCHEMBL2018096Sodium/glucose cotransporter 2 inhibitorINHIBITORChEMBL

Trials 954

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07598864DAPAGLIFLOZINPHASE3ClinicalTrials.gov
NCT07595289DAPAGLIFLOZINClinicalTrials.gov
NCT07594145SOTAGLIFLOZINPHASE2ClinicalTrials.gov
NCT07591077EMPAGLIFLOZINPHASE2/PHASE3ClinicalTrials.gov
NCT07556094EMPAGLIFLOZINClinicalTrials.gov
NCT07555106DAPAGLIFLOZINPHASE2ClinicalTrials.gov
NCT07539259DAPAGLIFLOZINPHASE2ClinicalTrials.gov
NCT07516847DAPAGLIFLOZINPHASE2ClinicalTrials.gov
NCT07515391DAPAGLIFLOZINPHASE2ClinicalTrials.gov
NCT07491718DAPAGLIFLOZINClinicalTrials.gov

NIH grants 2530

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
UL1TR001863Yale Clinical and Translational Science Award302,025NIH's project files
P30DK045735Yale Diabetes Research Center262,025NIH's project files
R01DK112042Glomerular and Tubular Function in the Diabetic Kidney202,025NIH's project files
U54GM104940Louisiana Clinical and Translational Science Center202,025NIH's project files
P30DK036836Diabetes Research Center162,025NIH's project files
P30DK020572Michigan Diabetes Research Center (MDRC)152,025NIH's project files
P30DK017047Diabetes Research Center132,025NIH's project files
P30DK020541NYR-Diabetes Research Center (NYR-DRC)132,025NIH's project files
P30CA008748Cancer Center Support Grant122,025NIH's project files
P30DK079626UAB Diabetes Research Center122,025NIH's project files

Papers 16493

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42826278PubTator, text miningPubMed
42826222PubTator, text miningPubMed
42826142PubTator, text miningPubMed
42824439PubTator, text miningPubMed
42821207PubTator, text miningPubMed
42821047PubTator, text miningPubMed
42820470PubTator, text miningPubMed
42818421PubTator, text miningPubMed
42817877PubTator, text miningPubMed
42817074PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license