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NCF1: neutrophil cytosolic factor 1

1 protein, 9 patents, 0 drugs, 0 trials, 3,085 NIH grants and 5,369 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolNCF1HGNC
Nameneutrophil cytosolic factor 1HGNC
NCBI Gene ID653361NCBI Gene
HGNC IDHGNC:7660HGNC
EnsemblENSG00000158517NCBI Gene
AliasesCGD1, NCF-1, NCF-47K, NCF1A, NOXO2, SH3PXD1A, p47-phox, p47phoxNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P14598Neutrophil cytosol factor 139011Ensembl, GeneID, HGNCUniProt

Patents 9

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4373939 A22024-05-2934422P14598Espacenet
JP 2023527622 A2023-06-302P14598Espacenet
KR 1020230015923 A2023-01-312P14598Espacenet
US 11446398 B22022-09-2056729P14598Espacenet
JP 2022524081 A2022-04-27159700P14598Espacenet
US 11078247 B22021-08-037301P14598Espacenet
WO 2019161400 A12019-08-229P14598Espacenet
WO 2019161400 A12019-08-2217P14598Espacenet
EP 1583820 A22005-10-12451P14598Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 3085

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
ZIAAI000646Transgenic Animal Models Of Human Immune Defects462,025NIH's project files
ZIAAI000645Development and Clinical Application of Gene and Cell therapies for Patients with Immune Deficiencies282,025NIH's project files
ZIAAI000644Gene Therapy and Hematopoietic Stem Cell Research to Treat Inherited Primary Immune Deficiencies262,025NIH's project files
P30CA016672Cancer Center Support Grant82,025NIH's project files
ZIAAI000647Genes And Gene Products As Immunoadjuvants82,025NIH's project files
ZIAAI000989Development and conduct of allogeneic stem cell transplant and autologous stem cell gene therapy for inherited immune deficiencies82,025NIH's project files
P30CA016056Roswell Park Cancer Center Support Grant72,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award72,025NIH's project files
ZIABC010677NADPH Oxidases as Novel Targets for Cancer Therapy72,025NIH's project files
P50AA011999Southern California Research Center for ALPD and Cirrhosis62,025NIH's project files

Papers 5369

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42806133PubTator, text miningPubMed
42792177PubTator, text miningPubMed
42758005PubTator, text miningPubMed
42667656PubTator, text miningPubMed
42661778PubTator, text miningPubMed
42637892PubTator, text miningPubMed
42630363PubTator, text miningPubMed
42589358PubTator, text miningPubMed
42540628PubTator, text miningPubMed
42539096PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license