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SFTPA1: surfactant protein A1

1 protein, 86 patents, 0 drugs, 0 trials, 2,427 NIH grants and 6,201 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolSFTPA1HGNC
Namesurfactant protein A1HGNC
NCBI Gene ID653509NCBI Gene
HGNC IDHGNC:10798HGNC
EnsemblENSG00000122852NCBI Gene
AliasesCOLEC4, ILD1, PSP-A, PSPA, SFTP1, SFTPA1B, SP-A, SP-A1, SP-A1 beta, SP-A1 delta, SP-A1 epsilon, SP-A1 gamma, SPA, SPA1NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q8IWL2Pulmonary surfactant-associated protein A12480Ensembl, GeneID, HGNCUniProt

Patents 86

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1465897Q8IWL2Espacenet
JP 2026004568 A2026-01-1465898Q8IWL2Espacenet
JP 2026004568 A2026-01-1465900Q8IWL2Espacenet
WO 2025262255 A12025-12-267Q8IWL2Espacenet
EP 4650780 A22025-11-1911614Q8IWL2Espacenet
JP 2025147176 A2025-10-0612166Q8IWL2Espacenet
JP 2025147176 A2025-10-0612167Q8IWL2Espacenet
JP 2025529142 A2025-09-047702Q8IWL2Espacenet
US 12371689 B22025-07-297702Q8IWL2Espacenet
JP 2025517970 A2025-06-1211614Q8IWL2Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 2427

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
R01HL031197Mitochondrial DNA Injury is a Key Contributor to the Development of Chemical Lung Injury132,025NIH's project files
U19AI125357Innate Immunity and Viral Infection in Asthma112,025NIH's project files
P30ES013508Center of Excellence in Environmental Toxicology92,025NIH's project files
P30CA008748Cancer Center Support Grant82,025NIH's project files
P30ES005605Environmental Health Sciences Research Center82,025NIH's project files
R01AI052474Vaccine Assembly from Surface Proteins of Staphylococcus aureus82,025NIH's project files
R01HL095993Derivation of lung epithelia from iPS cells for advanced disease modeling82,025NIH's project files
ZIAHD002400The Role Of Subclinical Infection And Cytokines In Preterm Parturition82,025NIH's project files
P30ES006694Southwest Environmental Health Sciences Center62,025NIH's project files
R01HL077612Precision phenotyping of emphysema in the elderly: the MESA Lung Study62,025NIH's project files

Papers 6201

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42809011PubTator, text miningPubMed
42795769PubTator, text miningPubMed
42753231PubTator, text miningPubMed
42747748PubTator, text miningPubMed
42745856PubTator, text miningPubMed
42715026PubTator, text miningPubMed
42698575PubTator, text miningPubMed
42694925PubTator, text miningPubMed
42693576PubTator, text miningPubMed
42674174PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license