Gene · 6536
SLC6A9: solute carrier family 6 member 9
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. SLC6A9: solute carrier family 6 member 9. Genes, record 6536. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6536
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P48067 | Sodium- and chloride-dependent glycine transporter 1 | 706 | 9 | Ensembl, GeneID, HGNC |
Source UniProt
Patents24
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026067851 A | 2026-04-21 | 332 | P48067 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 64774 | P48067 | Espacenet |
| EP 4641202 A2 | 2025-10-29 | 427 | P48067 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 12430 | P48067 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 4294 | P48067 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 7741 | P48067 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 4294 | P48067 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 7741 | P48067 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 12430 | P48067 | Espacenet |
| KR 1020250017231 A | 2025-02-04 | 427 | P48067 | Espacenet |
1 to 10 of 24
See all 24 patentsDrugs3
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
Trials23
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
| Trial | Drug | Phase | Results first posted | Source |
|---|---|---|---|---|
| NCT07603401 | BITOPERTIN | ClinicalTrials.gov | ||
| NCT07123363 | BITOPERTIN | PHASE1 | ClinicalTrials.gov | |
| NCT06910358 | BITOPERTIN | PHASE3 | ClinicalTrials.gov | |
| NCT05883748 | BITOPERTIN | PHASE2/PHASE3 | ClinicalTrials.gov | |
| NCT05828108 | BITOPERTIN | PHASE1/PHASE2 | ClinicalTrials.gov | |
| NCT05308472 | BITOPERTIN | PHASE2 | 2026-01-08 | ClinicalTrials.gov |
| NCT03271541 | BITOPERTIN | PHASE2 | ClinicalTrials.gov | |
| NCT01911676 | PF-03463275 | PHASE2 | 2023-02-27 | ClinicalTrials.gov |
| NCT01674361 | BITOPERTIN | PHASE2 | ClinicalTrials.gov | |
| NCT01235585 | BITOPERTIN | PHASE3 | ClinicalTrials.gov |
1 to 10 of 23
See all 23 trialsNIH grants651
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | SLC6A9 papers | Newest fiscal year |
|---|---|---|---|
| UL1TR001863 | Yale Clinical and Translational Science Award | 7 | 2025 |
| U10AA008401 | Collaborative Study on the Genetics of Alcoholism (COGA). | 4 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 3 | 2025 |
| P30DK058404 | Molecular and Cellular Basis for Digestive Diseases | 3 | 2025 |
| P30EY008126 | Core Grant in Vision Research | 3 | 2025 |
| P50AA012870 | Center for the Translational Neuroscience of Alcoholism | 3 | 2025 |
| R01MH062646 | Regulation of Signaling by mGluR5 | 3 | 2025 |
| R01NS031373 | Functions of Metabotropic Glutamate Receptor Subtypes | 3 | 2025 |
| P30CA016058 | Cancer Center Support Grant | 2 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 2 | 2025 |
1 to 10 of 651Source NIH's project files
See all 651 nih grantsPapers985
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Multi criteria evaluation of schizophrenia drugs: DFT, ADMET, and molecular docking investigations. | Comput Biol Chem | 2026 | 42800397 | PubTator, text mining | PubMed |
| Novel SLC6A9 variants in an adult presenting with GlyT1 encephalopathy. | J Hum Genet | 2026 | 42728308 | PubTator, text mining | PubMed |
| Targeting glycine transporter type 1 (GlyT1) in epilepsy: Pathophysiological rationale and therapeutic perspectives. | Pharmacol Ther | 2026 | 42668023 | PubTator, text mining | PubMed |
| Results from the first clinical trial of bitopertin for steroid-relapsed/refractory Diamond-Blackfan anemia. | Blood Red Cells Iron | 2026 | 42583025 | PubTator, text mining | PubMed |
| Emerging non-D2 receptor-based therapies for schizophrenia: a focus on muscarinic and glutamatergic pathways. | Front Psychiatry | 2026 | 42500322 | PubTator, text mining | PubMed |
| Pharmacokinetic/pharmacodynamic analysis to characterize the effect of long-term GlyT1 inhibitor iclepertin exposure on hemoglobin levels. | Front Pharmacol | 2026 | 42499503 | PubTator, text mining | PubMed |
| Clinicopathological and molecular characterization of HPV-associated cervical poorly cohesive carcinoma: a rare aggressive entity. | J Pathol Clin Res | 2026 | 42289532 | PubTator, text mining | PubMed |
| Accelerated Sampling of Protein Dynamics Using BioEmu-Augmented Molecular Simulation. | J Chem Inf Model | 2026 | 42268730 | PubTator, text mining | PubMed |
| Dendrobine inhibits the growth and invasion of human breast cancer cells by regulating the NF-κB signaling pathway via the SLC6A9 target. | Cytotechnology | 2026 | 42153166 | PubTator, text mining | PubMed |
| The Effect of Iclepertin on Hematological Parameters: An Overview of Nonclinical Studies and Clinical Trials in Healthy Volunteers and Patients with Cognitive Impairment Associated with Schizophrenia. | J Clin Pharmacol | 2026 | 42053463 | PubTator, text mining | PubMed |
1 to 10 of 985
See all 985 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/6536
GET https://conductscience.org/api/genes/v1/6536/patents?page=2