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Gene · 654

BMP6: bone morphogenetic protein 6

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. BMP6: bone morphogenetic protein 6. Genes, record 654. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/654

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Gene

Symbol
BMP6
HGNC
Name
bone morphogenetic protein 6
HGNC
NCBI Gene ID
654
NCBI Gene
HGNC ID
HGNC:1073
HGNC
Ensembl
ENSG00000153162
NCBI Gene
Aliases
IO, VGR, VGR1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P22004Bone morphogenetic protein 65135Ensembl, GeneID, HGNC

Source UniProt

Patents132

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4705273 A22026-03-11174P22004Espacenet
WO 2026017857 A12026-01-2217P22004Espacenet
WO 2026017864 A12026-01-2217P22004Espacenet
JP 2026004568 A2026-01-1439074P22004Espacenet
EP 4650780 A22025-11-193193P22004Espacenet
JP 2025147176 A2025-10-061502P22004Espacenet
JP 2025138816 A2025-09-2540P22004Espacenet
JP 2025529142 A2025-09-045593P22004Espacenet
EP 4606428 A22025-08-2731P22004Espacenet
JP 2025118644 A2025-08-131P22004Espacenet

1 to 10 of 132

See all 132 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,016

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleBMP6 papersNewest fiscal year
P30CA016672Cancer Center Support Grant102025
ZIADE000695Adeno-associated Virus Biology And Utilization For Gene Transfer82025
R01DK095112Regulatory Role of Transferrin in Erythropoiesis and Iron Metabolism72025
P30CA008748Cancer Center Support Grant62025
P30CA068485Cancer Center Support Grant52025
R01AR050452Skin Stem Cells and Their Niche Interactions52025
R01DE021475Development Genetics of Tooth Number Variation in Sticklebacks52025
UL1TR001863Yale Clinical and Translational Science Award52025
P30CA062203Cancer Center Support Grant42025
P30DK040561Boston Area Nutrition Obesity Research Center (NORC)42025

1 to 10 of 2,016Source NIH's project files

See all 2,016 nih grants

Papers3,545

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Cyclical Iron Homeostasis: The Role of Sex Hormones in Female Iron Regulation.Front Biosci (Landmark Ed)202642811967PubTator, text miningPubMed
Twist1 Promotes Endothelial Phenotypic Transition and Unstable Plaque Phenotype During Atherosclerosis.Arterioscler Thromb Vasc Biol202642689320PubTator, text miningPubMed
Whole-genome resequencing with multidimensional annotation revealed pathogenic networks in sirenomelia.Ital J Pediatr202642601645PubTator, text miningPubMed
Neurovascular-Immune Biomarkers in Ménière Disease: Insights From High-Throughput Proteomics.Otol Neurotol202642584982PubTator, text miningPubMed
Reimagining VEGF Therapy: The Role of PLCγ2 in Pan-Organ Endothelial Networks.Adv Wound Care (New Rochelle)202642552235PubTator, text miningPubMed
Investigating Novel Inflammatory Biomarkers and Pathways in Cardiac Cachexia.Heart Lung Circ202642521527PubTator, text miningPubMed
TaPIK3AP Regulates Female Reproduction in Tuta absoluta Through Juvenile Hormone-, Vitellogenin-, and TOR-Related Signaling.Insects202642505822PubTator, text miningPubMed
Methylation of the BMP6, BRCA1, ESR2, GSTP1 and TIMP3 genes in Mexican women with breast cancer and benign disease.Oncol Lett202642395267PubTator, text miningPubMed
Epigenetic regulation of the hepcidin gene expression in hepatoma cells.FEBS J202642387979PubTator, text miningPubMed
Beyond resorption: targeting osteoclast fusion and polarization to restore balanced bone remodeling.Front Pharmacol202642328629PubTator, text miningPubMed

1 to 10 of 3,545

See all 3,545 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/654

GET https://conductscience.org/api/genes/v1/654/patents?page=2