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Gene · 6541

SLC7A1: solute carrier family 7 member 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. SLC7A1: solute carrier family 7 member 1. Genes, record 6541. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6541

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Gene

Symbol
SLC7A1
HGNC
Name
solute carrier family 7 member 1
HGNC
NCBI Gene ID
6541
NCBI Gene
HGNC ID
HGNC:11057
HGNC
Ensembl
ENSG00000139514
NCBI Gene
Aliases
ATRC1, CAT-1, ERR, HCAT1, REC1L
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P30825High affinity cationic amino acid transporter 16290Ensembl, GeneID, HGNC

Source UniProt

Patents65

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026063215 A2026-04-10182P30825Espacenet
JP 2026004568 A2026-01-1464828P30825Espacenet
EP 4650780 A22025-11-1910366P30825Espacenet
JP 2025147176 A2025-10-0616548P30825Espacenet
JP 2025529142 A2025-09-044295P30825Espacenet
US 12371689 B22025-07-294295P30825Espacenet
JP 2025517970 A2025-06-1210366P30825Espacenet
JP 2025032204 A2025-03-1136063P30825Espacenet
JP 2025028160 A2025-02-2816548P30825Espacenet
KR 1020250010750 A2025-01-2116548P30825Espacenet

1 to 10 of 65

See all 65 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,292

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleSLC7A1 papersNewest fiscal year
P30CA016672Cancer Center Support Grant82025
P30DK058404Molecular and Cellular Basis for Digestive Diseases72025
P30AG024832UTMB Claude D. Pepper Older Americans Independence Center62025
T32DK007673Training in Gastroenterology62025
P01CA116087H. pylori-induced Inflammation and Gastric Cancer52025
P30CA051008Georgetown University Lombardi Comprehensive Cancer Center Support Grant52025
ZIAAG000393Influence of Post-transcriptional Gene Regulation on Cell Senescence and Aging52025
P30DK019525University of Pennsylvania Diabetes Research Center42025
R01DK060596Translational control by nutrients42025
T32CA009686Training Grant In Tumor Biology42025

1 to 10 of 1,292Source NIH's project files

See all 1,292 nih grants

Papers1,770

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Metabolic profiling of CAR T-cells in patients reveals a shift toward amino acid-supported OXPHOS and informs transporter engineering.Res Sq202642780275PubTator, text miningPubMed
Sakuranetin modulates estrogen receptor signaling in breast cancer cells.J Funct Foods202642719784PubTator, text miningPubMed
Research progress on metabolic abnormalities in myocardial hypertrophy.Front Cardiovasc Med202642602298PubTator, text miningPubMed
RanBP2 promotes ferroptosis resistance and compromises therapeutic response by stabilizing SLC7A1 through LRSAM1 SUMOylation and ubiquitination in lung adenocarcinoma.Cell Death Differ202642557375PubTator, text miningPubMed
Drinking Slightly Acidic Electrolyzed Water Promotes Growth Performance, Improves Digestion, and Modulates Antioxidant Status in Weaned Piglets.Animals (Basel)202642511002PubTator, text miningPubMed
Dynamic regulation of lysine and arginine metabolism promotes immune evasion by limiting T cell function in cancer.Sci Immunol202642497246PubTator, text miningPubMed
Activation-induced SLC7A1 expression enhances T cell sensitivity to cGAMP-mediated STING signaling.Cell Rep202642329763PubTator, text miningPubMed
Orphan nuclear receptors: structural mechanisms, ligand discovery, and therapeutic potential.Cell Signal202642250787PubTator, text miningPubMed
A Causality-Informed Correlation-Aware Health-State Assessment for Complex Equipment.Entropy (Basel)202642187947PubTator, text miningPubMed
circ-FSCN1 affects ferroptosis and cell viability in NSCLC via the miR-506-3p/SLC7A1 pathway.Transl Oncol202642107319PubTator, text miningPubMed

1 to 10 of 1,770

See all 1,770 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/6541

GET https://conductscience.org/api/genes/v1/6541/patents?page=2