Gene · 6541
SLC7A1: solute carrier family 7 member 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. SLC7A1: solute carrier family 7 member 1. Genes, record 6541. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6541
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P30825 | High affinity cationic amino acid transporter 1 | 629 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents65
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026063215 A | 2026-04-10 | 182 | P30825 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 64828 | P30825 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 10366 | P30825 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 16548 | P30825 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 4295 | P30825 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 4295 | P30825 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 10366 | P30825 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 36063 | P30825 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 16548 | P30825 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 16548 | P30825 | Espacenet |
1 to 10 of 65
See all 65 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,292
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | SLC7A1 papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 8 | 2025 |
| P30DK058404 | Molecular and Cellular Basis for Digestive Diseases | 7 | 2025 |
| P30AG024832 | UTMB Claude D. Pepper Older Americans Independence Center | 6 | 2025 |
| T32DK007673 | Training in Gastroenterology | 6 | 2025 |
| P01CA116087 | H. pylori-induced Inflammation and Gastric Cancer | 5 | 2025 |
| P30CA051008 | Georgetown University Lombardi Comprehensive Cancer Center Support Grant | 5 | 2025 |
| ZIAAG000393 | Influence of Post-transcriptional Gene Regulation on Cell Senescence and Aging | 5 | 2025 |
| P30DK019525 | University of Pennsylvania Diabetes Research Center | 4 | 2025 |
| R01DK060596 | Translational control by nutrients | 4 | 2025 |
| T32CA009686 | Training Grant In Tumor Biology | 4 | 2025 |
1 to 10 of 1,292Source NIH's project files
See all 1,292 nih grantsPapers1,770
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Metabolic profiling of CAR T-cells in patients reveals a shift toward amino acid-supported OXPHOS and informs transporter engineering. | Res Sq | 2026 | 42780275 | PubTator, text mining | PubMed |
| Sakuranetin modulates estrogen receptor signaling in breast cancer cells. | J Funct Foods | 2026 | 42719784 | PubTator, text mining | PubMed |
| Research progress on metabolic abnormalities in myocardial hypertrophy. | Front Cardiovasc Med | 2026 | 42602298 | PubTator, text mining | PubMed |
| RanBP2 promotes ferroptosis resistance and compromises therapeutic response by stabilizing SLC7A1 through LRSAM1 SUMOylation and ubiquitination in lung adenocarcinoma. | Cell Death Differ | 2026 | 42557375 | PubTator, text mining | PubMed |
| Drinking Slightly Acidic Electrolyzed Water Promotes Growth Performance, Improves Digestion, and Modulates Antioxidant Status in Weaned Piglets. | Animals (Basel) | 2026 | 42511002 | PubTator, text mining | PubMed |
| Dynamic regulation of lysine and arginine metabolism promotes immune evasion by limiting T cell function in cancer. | Sci Immunol | 2026 | 42497246 | PubTator, text mining | PubMed |
| Activation-induced SLC7A1 expression enhances T cell sensitivity to cGAMP-mediated STING signaling. | Cell Rep | 2026 | 42329763 | PubTator, text mining | PubMed |
| Orphan nuclear receptors: structural mechanisms, ligand discovery, and therapeutic potential. | Cell Signal | 2026 | 42250787 | PubTator, text mining | PubMed |
| A Causality-Informed Correlation-Aware Health-State Assessment for Complex Equipment. | Entropy (Basel) | 2026 | 42187947 | PubTator, text mining | PubMed |
| circ-FSCN1 affects ferroptosis and cell viability in NSCLC via the miR-506-3p/SLC7A1 pathway. | Transl Oncol | 2026 | 42107319 | PubTator, text mining | PubMed |
1 to 10 of 1,770
See all 1,770 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/6541
GET https://conductscience.org/api/genes/v1/6541/patents?page=2