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SLC8A1: solute carrier family 8 member A1

1 protein, 63 patents, 0 drugs, 0 trials, 2,774 NIH grants and 4,974 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolSLC8A1HGNC
Namesolute carrier family 8 member A1HGNC
NCBI Gene ID6546NCBI Gene
HGNC IDHGNC:11068HGNC
EnsemblENSG00000183023NCBI Gene
AliasesNCX1NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P32418Sodium/calcium exchanger 19735Ensembl, GeneID, HGNCUniProt

Patents 63

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1464840P32418Espacenet
JP 2026004568 A2026-01-1464841P32418Espacenet
JP 2026004568 A2026-01-1464843P32418Espacenet
EP 4641201 A22025-10-295733P32418Espacenet
JP 2025147176 A2025-10-0612438P32418Espacenet
JP 2025147176 A2025-10-0612443P32418Espacenet
JP 2025529142 A2025-09-044308P32418Espacenet
JP 2025529142 A2025-09-047742P32418Espacenet
US 12371689 B22025-07-294308P32418Espacenet
US 12371689 B22025-07-297742P32418Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 2774

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
R01HL131517Sex-specific arrhythmogenic mechanisms of atrial fibrillation112,025NIH's project files
R01HL136389The Role of Gasdermin-D/Interleukin-1 Nexus in Atrial Arrhythmogenesis82,025NIH's project files
P01HL141084Multiscale Systems to Elucidate Susceptibility and Cardioprotective Mechanisms in Cardio-oncology62,025NIH's project files
R01NS048216Na/H Exchanger in Microglial Metabolism and Function62,025NIH's project files
ZIAAG000844Stochastic Simulation Of Excitation-contraction Coupling62,025NIH's project files
R01HL076485Engineering Vascularized Cardiac Muscle52,025NIH's project files
ZIAAG000598Beat to beat Ca2+-dependent regulation of pacemaker cell rate and rhythm52,025NIH's project files
P01HL134608Exosomes as mediators of cardiac injury and repair42,025NIH's project files
P30DK063491Diabetes Research Center (DRC)42,025NIH's project files
R01HL141214Functional Microdomains in the Heart's Pacemaker: A New Dimension of Cardiac Remodeling42,025NIH's project files

Papers 4974

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42824453PubTator, text miningPubMed
42818031PubTator, text miningPubMed
42784236PubTator, text miningPubMed
42769728PubTator, text miningPubMed
42684683PubTator, text miningPubMed
42678620PubTator, text miningPubMed
42676393PubTator, text miningPubMed
42663306PubTator, text miningPubMed
42658530PubTator, text miningPubMed
42644057PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license