Gene · 6548
SLC9A1: solute carrier family 9 member A1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. SLC9A1: solute carrier family 9 member A1. Genes, record 6548. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6548
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P19634 | Sodium/hydrogen exchanger 1 | 815 | 20 | Ensembl, GeneID, HGNC |
Source UniProt
Patents34
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 64861 | P19634 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 2280 | P19634 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 4312 | P19634 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 4312 | P19634 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 2280 | P19634 | Espacenet |
| JP 2023086836 A | 2023-06-22 | 97 | P19634 | Espacenet |
| JP 2023505833 A | 2023-02-13 | 97 | P19634 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 82213 | P19634 | Espacenet |
| US 11400116 B2 | 2022-08-02 | 7322 | P19634 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 185184 | P19634 | Espacenet |
1 to 10 of 34
See all 34 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,862
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | SLC9A1 papers | Newest fiscal year |
|---|---|---|---|
| R01NS048216 | Na/H Exchanger in Microglial Metabolism and Function | 25 | 2025 |
| P30CA076292 | Moffitt Cancer Center Support Grant | 7 | 2025 |
| P30DK042086 | Center for Interdisciplinary Study of Inflammatory Intestinal DIsorders (C-IID) | 7 | 2025 |
| R01DK067528 | Mechanisms of Tubular Atrophy | 7 | 2025 |
| R01CA197855 | Roles for Intracellular pH Dynamics in Cancer | 6 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 5 | 2025 |
| P30DK034854 | Integrated Epithelial and Muscosal Biology | 5 | 2025 |
| P50CA211015 | UCLA SPORE in Brain Cancer | 4 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 3 | 2025 |
| P30CA010815 | Consolidated Basic Cancer Research Program | 3 | 2025 |
1 to 10 of 1,862Source NIH's project files
See all 1,862 nih grantsPapers3,457
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Inhibition of NHE1 Overcomes Temozolomide-Resistance in Glioblastoma via ROS-AKT/ERK Axis-Mediated Autophagy Suppression. | J Biochem Mol Toxicol | 2026 | 42740476 | PubTator, text mining | PubMed |
| Macrophage Dab1 Links Early Hypoxia to Adaptive Angiogenesis to Drive Peripheral Nerve Repair. | Adv Sci (Weinh) | 2026 | 42723198 | PubTator, text mining | PubMed |
| Cardiomyocyte calcium homeostasis remodeling in diabetes-related HFpEF: mechanisms and therapeutic perspectives. | Pharmacol Res | 2026 | 42697419 | PubTator, text mining | PubMed |
| Revising NHE-1: From Cardiac Homeostasis to Heart Failure and Future Drug Development. | Cell Biochem Funct | 2026 | 42677384 | PubTator, text mining | PubMed |
| NHE1 in Gastrointestinal Inflammation and Cancer: A Double-Edged Regulator. | Dig Dis Sci | 2026 | 42635895 | PubTator, text mining | PubMed |
| Genetically predicted triglyceride levels and endometriosis risk: Mendelian randomization with exploratory multi-omics analyses. | PLoS One | 2026 | 42594068 | PubTator, text mining | PubMed |
| CD44-targeting small-molecule inhibitors restore hyaluronan homeostasis and reduce profibrotic matrix remodeling in vocal fold fibroblasts exposed to cigarette smoke extract. | Toxicology | 2026 | 42562202 | PubTator, text mining | PubMed |
| Recent progress in small molecules targeting the acidic tumor microenvironment. | J Enzyme Inhib Med Chem | 2026 | 42550763 | PubTator, text mining | PubMed |
| Biomarker-guided pharmacotherapy in cardiovascular-kidney-metabolic syndrome: A three-dimensional framework for precision drug selection and monitoring. | Pharmacol Ther | 2026 | 42492739 | PubTator, text mining | PubMed |
| DLK1-35 Contributes to Temozolomide Resistance in Glioblastoma Through the miR-140-3p/NHE1/ERK-MGMT Axis. | Tohoku J Exp Med | 2026 | 42486642 | PubTator, text mining | PubMed |
1 to 10 of 3,457
See all 3,457 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/6548
GET https://conductscience.org/api/genes/v1/6548/patents?page=2