Gene · 6556
SLC11A1: solute carrier family 11 member 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. SLC11A1: solute carrier family 11 member 1. Genes, record 6556. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6556
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P49279 | Natural resistance-associated macrophage protein 1 | 550 | 2 | Ensembl, GeneID, HGNC |
Source UniProt
Patents23
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 63965 | P49279 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 595 | P49279 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 3986 | P49279 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 3986 | P49279 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 595 | P49279 | Espacenet |
| US 12006548 B2 | 2024-06-11 | 464 | P49279 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 80327 | P49279 | Espacenet |
| US 11400116 B2 | 2022-08-02 | 166 | P49279 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 183298 | P49279 | Espacenet |
| US 11078247 B2 | 2021-08-03 | 10331 | P49279 | Espacenet |
1 to 10 of 23
See all 23 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants955
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | SLC11A1 papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 4 | 2025 |
| P30CA046592 | University of Michigan Rogel Cancer Center Support Grant 2023-2028 | 4 | 2025 |
| R01AI073843 | Pathobiology of heme inducible transporters in Gram positive pathogens | 4 | 2025 |
| R01AI101171 | Host-mediated zinc sequestration during Acinetobacter baumannii infection | 4 | 2025 |
| R01AI116059 | Mechanisms of persistent Salmonella infection | 4 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 3 | 2025 |
| P30DK040561 | Boston Area Nutrition Obesity Research Center (NORC) | 3 | 2025 |
| R01AI055472 | Host Cell Signaling Pathways Induced by Salmonella | 3 | 2025 |
| R01ES010563 | Mechanisms of Manganese Neurotoxicity | 3 | 2025 |
| U01DK062413 | Determining genomic and host-environment contributions to IBD phenotypes | 3 | 2025 |
1 to 10 of 955Source NIH's project files
See all 955 nih grantsPapers2,059
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Multilevel Mechanisms by Which Membrane Transport Proteins Regulate Plant Responses to Heavy Metal Stress: From Ion Perception and Uptake Control to Systemic Signaling and Translational Perspectives. | Plant Cell Environ | 2026 | 42782210 | PubTator, text mining | PubMed |
| Genetic Variants of NRAMP1 and Hepcidin (HAMP) in Cancer Patients Infected with Human Herpesvirus-6. | Viral Immunol | 2026 | 42752297 | PubTator, text mining | PubMed |
| Melatonin as a hub signal integrating redox and hormonal crosstalk with multi-omics regulation in plant heavy metal stress tolerance. | Plant Physiol Biochem | 2026 | 42731282 | PubTator, text mining | PubMed |
| LsNAC72 from a major QTL activates LsNRAMP7 expression to promote iron accumulation in lettuce. | Plant Physiol | 2026 | 42635652 | PubTator, text mining | PubMed |
| Decoding macrophage-driven tumor heterogeneity in renal cell carcinoma using spatial and single-cell transcriptomics. | Transl Oncol | 2026 | 42580154 | PubTator, text mining | PubMed |
| Evaluation of the SLC11A1 non-synonymous variant rs17235409 and tuberculosis susceptibility in a multi-ethnic population from southwestern China. | Medicine (Baltimore) | 2026 | 42470058 | PubTator, text mining | PubMed |
| Harnessing biostimulants to alleviate potentially toxic element stress in vegetable crops. | Planta | 2026 | 42463972 | PubTator, text mining | PubMed |
| CXCL10/SLC11A1 Axis Exacerbates Septic Liver Injury by Regulating Neutrophil Extracellular Traps Formation to Drive Macrophage Pro‑Inflammatory Polarization. | Adv Sci (Weinh) | 2026 | 42439546 | PubTator, text mining | PubMed |
| Transporter promiscuity and redox-driven metal partitioning in plant responses to chemically analogous metals. | Plant Cell Rep | 2026 | 42329452 | PubTator, text mining | PubMed |
| An N-terminal amphipathic helix governs activity and conformational dynamics of Nramp metal transporters. | J Biol Chem | 2026 | 42264089 | PubTator, text mining | PubMed |
1 to 10 of 2,059
See all 2,059 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/6556
GET https://conductscience.org/api/genes/v1/6556/patents?page=2