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SLC22A2: solute carrier family 22 member 2
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Gene · 6582

Papers2,540

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

1 to 20 of 2,540

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TitleJournalYearPMIDFound bySource
Creatinine-Cystatin C Discrepancy and Renal Transporter Polymorphisms in Japanese Patients with Breast Cancer Receiving Abemaciclib.Clin Pharmacol Ther202642773505PubTator, text miningPubMed
Evodiamine alleviates CUMS-induced depressive-like behaviours associated with modulation of uptake-2 transporters.Xenobiotica202642728579PubTator, text miningPubMed
Pharmacogenomics of dolutegravir: A scoping review of evidence, gaps and clinical implications.Br J Clin Pharmacol202642521219PubTator, text miningPubMed
From Genotype to Phenotype: Investigating SLC22A5 Variants and Their Significance in Carnitine Deficiency: A Systematic Review Study.J Cell Mol Med202642480505PubTator, text miningPubMed
Transporter gene variants influencing metformin pharmacokinetics and pharmacodynamics common in European populations: a pharmacogenetic narrative review.Front Pharmacol202642403712PubTator, text miningPubMed
Effects of Trimethoprim on Three Previously Proposed Putative Biomarkers for OCT2/MATE-Mediated Renal Drug-Drug Interactions in Healthy Volunteers.Clin Pharmacol Ther202642400553PubTator, text miningPubMed
Identification of high-risk SNPs in SLC22A transporter genes: their potential role in PCOS and metformin uptake.BMC Genom Data202642310538PubTator, text miningPubMed
A whole genomic CRISPR-Cas9 screen identifies the amino acid transporter SLC43A1 (LAT3) as a major determinant of oxaliplatin sensitivity in colorectal cancer cells.Mol Cancer Ther202642227585PubTator, text miningPubMed
Regulation of Human Renal Transporters by Pregnancy-Related Hormones in Primary Proximal Tubular Epithelial Cells.Metabolites202642188001PubTator, text miningPubMed
Reduction in estimated glomerular filtration rate observed with doravirine is caused by inhibition of organic cation transporter 2.Drug Metab Dispos202642150384PubTator, text miningPubMed
Shared Genetic Liability Between Heart Failure and Myocardial Infarction Revealed by Genome-Wide Cross-Trait Analysis.J Cardiovasc Pharmacol Ther202642141940PubTator, text miningPubMed
MegaTrans-machine learning models for drug transporters corresponding to the FDA guidance.Drug Metab Dispos202642090811PubTator, text miningPubMed
Impact of renal hypoxia on OAT1 expression and adefovir-induced cytotoxicity in human 3D-RPTEC spheroids.Toxicol Appl Pharmacol202641936985PubTator, text miningPubMed
Identification of Brimonidine as a Novel Substrate of Organic Cation Transporters OCT2 and MATE1 Expressed in Human Eye.Invest Ophthalmol Vis Sci202641925694PubTator, text miningPubMed
Gabapentin CNS exposure and analgesic response are modulated by OCT2 genotype in patients with chronic neuropathic pain.Front Pharmacol202641908817PubTator, text miningPubMed
Drug-drug interaction assessments of clinical transporter inhibition: Learnings from the Transporter Working Group of the International Consortium for Innovation and Quality in Pharmaceutical Development.
Drug Metab Dispos202641894930PubTator, text miningPubMed
Inflammation: The Pathological Axis of Cisplatin-Induced Renal Injury.J Inflamm Res202641877823PubTator, text miningPubMed
Dynamic changes of the immune microenvironment in ovarian cancer following neoadjuvant chemotherapy.Cell Death Discov202641872134PubTator, text miningPubMed
Solute carrier-mediated membrane transport of hepatotoxic phytochemicals and synthetic drugs.Life Sci202641862051PubTator, text miningPubMed
The 2-Amino-3,4-dihydroquinazoline Molecular Scaffold as Novel OCT3 Inhibitor.ACS Chem Neurosci202641856981PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

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Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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