Gene · 6582
SLC22A2: solute carrier family 22 member 2
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. SLC22A2: solute carrier family 22 member 2. Genes, record 6582. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6582
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| O15244 | Solute carrier family 22 member 2 | 555 | 1 | Ensembl, GeneID, HGNC |
Source UniProt
Patents41
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| US 12534732 B2 | 2026-01-27 | 921 | O15244 | Espacenet |
| JP 2026012378 A | 2026-01-23 | 921 | O15244 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 64186 | O15244 | Espacenet |
| US 12516329 B2 | 2026-01-06 | 921 | O15244 | Espacenet |
| EP 4670792 A2 | 2025-12-31 | 921 | O15244 | Espacenet |
| KR 1020250160362 A | 2025-11-12 | 921 | O15244 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 8293 | O15244 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 4058 | O15244 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 4058 | O15244 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 8293 | O15244 | Espacenet |
1 to 10 of 41
See all 41 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,310
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | SLC22A2 papers | Newest fiscal year |
|---|---|---|---|
| P30ES006694 | Southwest Environmental Health Sciences Center | 23 | 2025 |
| P30CA021765 | Cancer Center Support Grant (CCSG) | 16 | 2025 |
| P30DK026743 | UCSF Liver Center | 8 | 2025 |
| R25CA023944 | PEDIATRIC ONCOLOGY EDUCATION (YEARS 38 - 42) | 8 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 7 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 7 | 2025 |
| T32ES007148 | Training in Environmental Toxicology | 6 | 2025 |
| T32GM007546 | Clinical Pharmacology, Drug Action and Pharmacogenetics | 6 | 2025 |
| T32HL007249 | Interdisciplinary Training in Cardiovascular Research | 6 | 2025 |
| P30ES005022 | Rutgers Center for Environmental Exposure and Disease (CEED) | 5 | 2025 |
1 to 10 of 1,310Source NIH's project files
See all 1,310 nih grantsPapers2,540
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Creatinine-Cystatin C Discrepancy and Renal Transporter Polymorphisms in Japanese Patients with Breast Cancer Receiving Abemaciclib. | Clin Pharmacol Ther | 2026 | 42773505 | PubTator, text mining | PubMed |
| Evodiamine alleviates CUMS-induced depressive-like behaviours associated with modulation of uptake-2 transporters. | Xenobiotica | 2026 | 42728579 | PubTator, text mining | PubMed |
| Pharmacogenomics of dolutegravir: A scoping review of evidence, gaps and clinical implications. | Br J Clin Pharmacol | 2026 | 42521219 | PubTator, text mining | PubMed |
| From Genotype to Phenotype: Investigating SLC22A5 Variants and Their Significance in Carnitine Deficiency: A Systematic Review Study. | J Cell Mol Med | 2026 | 42480505 | PubTator, text mining | PubMed |
| Transporter gene variants influencing metformin pharmacokinetics and pharmacodynamics common in European populations: a pharmacogenetic narrative review. | Front Pharmacol | 2026 | 42403712 | PubTator, text mining | PubMed |
| Effects of Trimethoprim on Three Previously Proposed Putative Biomarkers for OCT2/MATE-Mediated Renal Drug-Drug Interactions in Healthy Volunteers. | Clin Pharmacol Ther | 2026 | 42400553 | PubTator, text mining | PubMed |
| Identification of high-risk SNPs in SLC22A transporter genes: their potential role in PCOS and metformin uptake. | BMC Genom Data | 2026 | 42310538 | PubTator, text mining | PubMed |
| A whole genomic CRISPR-Cas9 screen identifies the amino acid transporter SLC43A1 (LAT3) as a major determinant of oxaliplatin sensitivity in colorectal cancer cells. | Mol Cancer Ther | 2026 | 42227585 | PubTator, text mining | PubMed |
| Regulation of Human Renal Transporters by Pregnancy-Related Hormones in Primary Proximal Tubular Epithelial Cells. | Metabolites | 2026 | 42188001 | PubTator, text mining | PubMed |
| Reduction in estimated glomerular filtration rate observed with doravirine is caused by inhibition of organic cation transporter 2. | Drug Metab Dispos | 2026 | 42150384 | PubTator, text mining | PubMed |
1 to 10 of 2,540
See all 2,540 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/6582
GET https://conductscience.org/api/genes/v1/6582/patents?page=2