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Gene · 6582

SLC22A2: solute carrier family 22 member 2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. SLC22A2: solute carrier family 22 member 2. Genes, record 6582. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6582

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Gene

Symbol
SLC22A2
HGNC
Name
solute carrier family 22 member 2
HGNC
NCBI Gene ID
6582
NCBI Gene
HGNC ID
HGNC:10966
HGNC
Ensembl
ENSG00000112499
NCBI Gene
Aliases
OCT2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O15244Solute carrier family 22 member 25551Ensembl, GeneID, HGNC

Source UniProt

Patents41

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
US 12534732 B22026-01-27921O15244Espacenet
JP 2026012378 A2026-01-23921O15244Espacenet
JP 2026004568 A2026-01-1464186O15244Espacenet
US 12516329 B22026-01-06921O15244Espacenet
EP 4670792 A22025-12-31921O15244Espacenet
KR 1020250160362 A2025-11-12921O15244Espacenet
EP 4641201 A22025-10-298293O15244Espacenet
JP 2025529142 A2025-09-044058O15244Espacenet
US 12371689 B22025-07-294058O15244Espacenet
JP 2025517969 A2025-06-128293O15244Espacenet

1 to 10 of 41

See all 41 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,310

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleSLC22A2 papersNewest fiscal year
P30ES006694Southwest Environmental Health Sciences Center232025
P30CA021765Cancer Center Support Grant (CCSG)162025
P30DK026743UCSF Liver Center82025
R25CA023944PEDIATRIC ONCOLOGY EDUCATION (YEARS 38 - 42)82025
P30CA008748Cancer Center Support Grant72025
P30CA016672Cancer Center Support Grant72025
T32ES007148Training in Environmental Toxicology62025
T32GM007546Clinical Pharmacology, Drug Action and Pharmacogenetics62025
T32HL007249Interdisciplinary Training in Cardiovascular Research62025
P30ES005022Rutgers Center for Environmental Exposure and Disease (CEED)52025

1 to 10 of 1,310Source NIH's project files

See all 1,310 nih grants

Papers2,540

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Creatinine-Cystatin C Discrepancy and Renal Transporter Polymorphisms in Japanese Patients with Breast Cancer Receiving Abemaciclib.Clin Pharmacol Ther202642773505PubTator, text miningPubMed
Evodiamine alleviates CUMS-induced depressive-like behaviours associated with modulation of uptake-2 transporters.Xenobiotica202642728579PubTator, text miningPubMed
Pharmacogenomics of dolutegravir: A scoping review of evidence, gaps and clinical implications.Br J Clin Pharmacol202642521219PubTator, text miningPubMed
From Genotype to Phenotype: Investigating SLC22A5 Variants and Their Significance in Carnitine Deficiency: A Systematic Review Study.J Cell Mol Med202642480505PubTator, text miningPubMed
Transporter gene variants influencing metformin pharmacokinetics and pharmacodynamics common in European populations: a pharmacogenetic narrative review.Front Pharmacol202642403712PubTator, text miningPubMed
Effects of Trimethoprim on Three Previously Proposed Putative Biomarkers for OCT2/MATE-Mediated Renal Drug-Drug Interactions in Healthy Volunteers.Clin Pharmacol Ther202642400553PubTator, text miningPubMed
Identification of high-risk SNPs in SLC22A transporter genes: their potential role in PCOS and metformin uptake.BMC Genom Data202642310538PubTator, text miningPubMed
A whole genomic CRISPR-Cas9 screen identifies the amino acid transporter SLC43A1 (LAT3) as a major determinant of oxaliplatin sensitivity in colorectal cancer cells.Mol Cancer Ther202642227585PubTator, text miningPubMed
Regulation of Human Renal Transporters by Pregnancy-Related Hormones in Primary Proximal Tubular Epithelial Cells.Metabolites202642188001PubTator, text miningPubMed
Reduction in estimated glomerular filtration rate observed with doravirine is caused by inhibition of organic cation transporter 2.Drug Metab Dispos202642150384PubTator, text miningPubMed

1 to 10 of 2,540

See all 2,540 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/6582

GET https://conductscience.org/api/genes/v1/6582/patents?page=2