Gene · 6584
SLC22A5: solute carrier family 22 member 5
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. SLC22A5: solute carrier family 22 member 5. Genes, record 6584. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6584
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| O76082 | Organic cation/carnitine transporter 2 | 557 | 3 | Ensembl, GeneID, HGNC |
Source UniProt
Patents51
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026067851 A | 2026-04-21 | 183 | O76082 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 64195 | O76082 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 1149 | O76082 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 4063 | O76082 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 4063 | O76082 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 1149 | O76082 | Espacenet |
| JP 2023521663 A | 2023-05-25 | 182 | O76082 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 80790 | O76082 | Espacenet |
| US 11408034 B2 | 2022-08-09 | 559 | O76082 | Espacenet |
| US 11400116 B2 | 2022-08-02 | 2779 | O76082 | Espacenet |
1 to 10 of 51
See all 51 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,047
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | SLC22A5 papers | Newest fiscal year |
|---|---|---|---|
| P30CA021765 | Cancer Center Support Grant (CCSG) | 7 | 2025 |
| U01FD005946 | University of Maryland Center of Excellence in Regulatory Science and Innovation | 7 | 2025 |
| P30ES006694 | Southwest Environmental Health Sciences Center | 6 | 2025 |
| P30ES005022 | Rutgers Center for Environmental Exposure and Disease (CEED) | 5 | 2025 |
| U01DK062413 | Determining genomic and host-environment contributions to IBD phenotypes | 5 | 2025 |
| U01DK062422 | Mount Sinai NYC Genetics Research Center: Multi-omic integration across data-types, cell niches and populations | 5 | 2025 |
| P30DK043351 | Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital | 4 | 2025 |
| P30ES007048 | Environmental Exposures, Host Factors and Human Disease | 4 | 2025 |
| R25CA023944 | PEDIATRIC ONCOLOGY EDUCATION (YEARS 38 - 42) | 4 | 2025 |
| T32ES007148 | Training in Environmental Toxicology | 4 | 2025 |
1 to 10 of 1,047Source NIH's project files
See all 1,047 nih grantsPapers1,762
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Integrated Multi-Tissue Omics Identifies Acylcarnitine Accumulation as Shared Metabolic Marker of Diabetic Microangiopathy With Cross-Organ Validation. | Invest Ophthalmol Vis Sci | 2026 | 42747258 | PubTator, text mining | PubMed |
| Construction of a human placental brush border membrane vesicle model for evaluating the effect of antenatal drugs on OCTN1/2 transport function. | Chem Biol Interact | 2026 | 42731662 | PubTator, text mining | PubMed |
| Lipid Metabolism-related lncRNA Model Identifies AC026412.3 as a Driver of Fatty Acid β-oxidation in Hepatocellular Carcinoma. | J Clin Transl Hepatol | 2026 | 42724077 | PubTator, text mining | PubMed |
| [Screening and genetic variation analysis of fatty acid oxidation disorder in neonates in Qingdao City]. | Zhongguo Dang Dai Er Ke Za Zhi | 2026 | 42608300 | PubTator, text mining | PubMed |
| Fetal Kabuki syndrome caused by a novel gene variation in KMT2D with primary carnitine deficiency: a case report. | J Med Case Rep | 2026 | 42482245 | PubTator, text mining | PubMed |
| From Genotype to Phenotype: Investigating SLC22A5 Variants and Their Significance in Carnitine Deficiency: A Systematic Review Study. | J Cell Mol Med | 2026 | 42480505 | PubTator, text mining | PubMed |
| Microbiome-associated metabolites, valerobetaine and homocarnitine, inhibit carnitine transport via OCTN2. | Am J Physiol Cell Physiol | 2026 | 42478782 | PubTator, text mining | PubMed |
| Neuroimmune Genetic Overlap Between Chronic Pruritic Skin Diseases and Major Depressive Disorder: Insights from Cross-Trait GWAS Analysis. | Clin Cosmet Investig Dermatol | 2026 | 42445668 | PubTator, text mining | PubMed |
| Sudden Cardiac Arrest and Takotsubo-Like Cardiomyopathy as the Initial Presentation of Primary Carnitine Deficiency. | JACC Case Rep | 2026 | 42400576 | PubTator, text mining | PubMed |
| Single-Cell Transcriptomics in Triple-Negative Breast Cancer: Implications for Radionuclide Therapy in Precision Oncology. | Cancer Biother Radiopharm | 2026 | 42338131 | PubTator, text mining | PubMed |
1 to 10 of 1,762
See all 1,762 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/6584
GET https://conductscience.org/api/genes/v1/6584/patents?page=2