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Gene · 6584

SLC22A5: solute carrier family 22 member 5

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. SLC22A5: solute carrier family 22 member 5. Genes, record 6584. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6584

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Gene

Symbol
SLC22A5
HGNC
Name
solute carrier family 22 member 5
HGNC
NCBI Gene ID
6584
NCBI Gene
HGNC ID
HGNC:10969
HGNC
Ensembl
ENSG00000197375
NCBI Gene
Aliases
CDSP, OCTN2, SCD
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O76082Organic cation/carnitine transporter 25573Ensembl, GeneID, HGNC

Source UniProt

Patents51

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026067851 A2026-04-21183O76082Espacenet
JP 2026004568 A2026-01-1464195O76082Espacenet
EP 4650780 A22025-11-191149O76082Espacenet
JP 2025529142 A2025-09-044063O76082Espacenet
US 12371689 B22025-07-294063O76082Espacenet
JP 2025517970 A2025-06-121149O76082Espacenet
JP 2023521663 A2023-05-25182O76082Espacenet
US 11446398 B22022-09-2080790O76082Espacenet
US 11408034 B22022-08-09559O76082Espacenet
US 11400116 B22022-08-022779O76082Espacenet

1 to 10 of 51

See all 51 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,047

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleSLC22A5 papersNewest fiscal year
P30CA021765Cancer Center Support Grant (CCSG)72025
U01FD005946University of Maryland Center of Excellence in Regulatory Science and Innovation72025
P30ES006694Southwest Environmental Health Sciences Center62025
P30ES005022Rutgers Center for Environmental Exposure and Disease (CEED)52025
U01DK062413Determining genomic and host-environment contributions to IBD phenotypes52025
U01DK062422Mount Sinai NYC Genetics Research Center: Multi-omic integration across data-types, cell niches and populations52025
P30DK043351Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital42025
P30ES007048Environmental Exposures, Host Factors and Human Disease42025
R25CA023944PEDIATRIC ONCOLOGY EDUCATION (YEARS 38 - 42)42025
T32ES007148Training in Environmental Toxicology42025

1 to 10 of 1,047Source NIH's project files

See all 1,047 nih grants

Papers1,762

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Integrated Multi-Tissue Omics Identifies Acylcarnitine Accumulation as Shared Metabolic Marker of Diabetic Microangiopathy With Cross-Organ Validation.Invest Ophthalmol Vis Sci202642747258PubTator, text miningPubMed
Construction of a human placental brush border membrane vesicle model for evaluating the effect of antenatal drugs on OCTN1/2 transport function.Chem Biol Interact202642731662PubTator, text miningPubMed
Lipid Metabolism-related lncRNA Model Identifies AC026412.3 as a Driver of Fatty Acid β-oxidation in Hepatocellular Carcinoma.J Clin Transl Hepatol202642724077PubTator, text miningPubMed
[Screening and genetic variation analysis of fatty acid oxidation disorder in neonates in Qingdao City].Zhongguo Dang Dai Er Ke Za Zhi202642608300PubTator, text miningPubMed
Fetal Kabuki syndrome caused by a novel gene variation in KMT2D with primary carnitine deficiency: a case report.J Med Case Rep202642482245PubTator, text miningPubMed
From Genotype to Phenotype: Investigating SLC22A5 Variants and Their Significance in Carnitine Deficiency: A Systematic Review Study.J Cell Mol Med202642480505PubTator, text miningPubMed
Microbiome-associated metabolites, valerobetaine and homocarnitine, inhibit carnitine transport via OCTN2.Am J Physiol Cell Physiol202642478782PubTator, text miningPubMed
Neuroimmune Genetic Overlap Between Chronic Pruritic Skin Diseases and Major Depressive Disorder: Insights from Cross-Trait GWAS Analysis.Clin Cosmet Investig Dermatol202642445668PubTator, text miningPubMed
Sudden Cardiac Arrest and Takotsubo-Like Cardiomyopathy as the Initial Presentation of Primary Carnitine Deficiency.JACC Case Rep202642400576PubTator, text miningPubMed
Single-Cell Transcriptomics in Triple-Negative Breast Cancer: Implications for Radionuclide Therapy in Precision Oncology.Cancer Biother Radiopharm202642338131PubTator, text miningPubMed

1 to 10 of 1,762

See all 1,762 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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