Gene · 660
BMX: BMX non-receptor tyrosine kinase
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. BMX: BMX non-receptor tyrosine kinase. Genes, record 660. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/660
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P51813 | Cytoplasmic tyrosine-protein kinase BMX | 675 | 6 | Ensembl, GeneID, HGNC |
Source UniProt
Patents83
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| US 12540940 B2 | 2026-02-03 | 45 | P51813 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 39046 | P51813 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 39047 | P51813 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 39048 | P51813 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 9243 | P51813 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 9244 | P51813 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 9245 | P51813 | Espacenet |
| US 12006548 B2 | 2024-06-11 | 336 | P51813 | Espacenet |
| US 11624747 B2 | 2023-04-11 | 45 | P51813 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 9243 | P51813 | Espacenet |
1 to 10 of 83
See all 83 patentsDrugs2
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
Trials24
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
| Trial | Drug | Phase | Results first posted | Source |
|---|---|---|---|---|
| NCT07228390 | RITLECITINIB | PHASE2 | ClinicalTrials.gov | |
| NCT07226531 | RITLECITINIB | ClinicalTrials.gov | ||
| NCT07200128 | RITLECITINIB | ClinicalTrials.gov | ||
| NCT07152626 | RITLECITINIB | PHASE2 | ClinicalTrials.gov | |
| NCT07152119 | RITLECITINIB TOSYLATE | ClinicalTrials.gov | ||
| NCT07029828 | RITLECITINIB | PHASE3 | ClinicalTrials.gov | |
| NCT07029711 | RITLECITINIB | PHASE3 | ClinicalTrials.gov | |
| NCT06873945 | RITLECITINIB | PHASE3 | ClinicalTrials.gov | |
| NCT06573593 | RITLECITINIB | ClinicalTrials.gov | ||
| NCT06531109 | RITLECITINIB | ClinicalTrials.gov |
1 to 10 of 24
See all 24 trialsNIH grants710
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | BMX papers | Newest fiscal year |
|---|---|---|---|
| R01AI043957 | Structural Studies of a T cell Specific Tyrosine Kinase | 12 | 2025 |
| P30CA016058 | Cancer Center Support Grant | 7 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 5 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 4 | 2025 |
| P30CA021765 | Cancer Center Support Grant (CCSG) | 4 | 2025 |
| P30CA093373 | Cancer Center Support Grant P30 | 4 | 2025 |
| P30CA006927 | Comprehensive Cancer Center Program at Fox Chase | 3 | 2025 |
| P30CA076292 | Moffitt Cancer Center Support Grant | 3 | 2025 |
| ZIAHL002346 | Tumor microenvironment in CLL and MCL: pathogenesis, targets, and therapy | 3 | 2025 |
| K12CA133250 | OSU K12 Training Grant in Oncology | 2 | 2025 |
1 to 10 of 710Source NIH's project files
See all 710 nih grantsPapers981
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Long-read, whole-genome sequencing and chemotherapy response of two patient-derived organoids from a TP53- and KRAS-mutant ovarian carcinoma. | bioRxiv | 2026 | 42465424 | PubTator, text mining | PubMed |
| Riding toward Selectivity: Optimization of Covalent 7-Azaindole-Based BMX Kinase Inhibitors. | J Med Chem | 2026 | 42441922 | PubTator, text mining | PubMed |
| Discovery of Dihydropyrimido-Pyrimidine-Based Bone Marrow Tyrosine Kinase Gene in Chromosome X Protein Proteolysis-Targeting Chimeras for the Treatment of Prostate Cancer. | ACS Med Chem Lett | 2026 | 42305213 | PubTator, text mining | PubMed |
| Comorbidity risk characteristics of rheumatoid arthritis in the context of depression-associated lipid metabolism. | Front Immunol | 2026 | 42273676 | PubTator, text mining | PubMed |
| Systematic analysis of programmed cell death-related genes in sepsis reveals immune heterogeneity and enables patient stratification. | Front Cell Dev Biol | 2026 | 42232056 | PubTator, text mining | PubMed |
| Targeting the BMX in cancer: molecular mechanisms and emerging therapeutic strategies. | J Enzyme Inhib Med Chem | 2026 | 42212521 | PubTator, text mining | PubMed |
| Identification of BMX as a Potential Biomarker for Rheumatoid Arthritis Based on WGCNA, Machine Learning, and Experimental Validation. | Immunol Invest | 2026 | 42204930 | PubTator, text mining | PubMed |
| BMX inhibition overcomes small cell lung cancer chemoresistance by stabilizing E2F1 via ERK1/2-Cyclin D1/CDK4/6 axis. | Signal Transduct Target Ther | 2026 | 41946708 | PubTator, text mining | PubMed |
| Discovery of Covalent Ligands with AlphaFold3. | J Am Chem Soc | 2026 | 41857796 | PubTator, text mining | PubMed |
| Systems biology analysis uncovers a ROS-associated gene signature and immunomodulatory role of CLEC4E in ischemic stroke. | PLoS One | 2026 | 41805714 | PubTator, text mining | PubMed |
1 to 10 of 981
See all 981 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/660
GET https://conductscience.org/api/genes/v1/660/patents?page=2