ConductScience.org, home

Gene · 660

BMX: BMX non-receptor tyrosine kinase

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. BMX: BMX non-receptor tyrosine kinase. Genes, record 660. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/660

On this page

Gene

Symbol
BMX
HGNC
Name
BMX non-receptor tyrosine kinase
HGNC
NCBI Gene ID
660
NCBI Gene
HGNC ID
HGNC:1079
HGNC
Ensembl
ENSG00000102010
NCBI Gene
Aliases
ETK, PSCTK2, PSCTK3
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P51813Cytoplasmic tyrosine-protein kinase BMX6756Ensembl, GeneID, HGNC

Source UniProt

Patents83

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
US 12540940 B22026-02-0345P51813Espacenet
JP 2026004568 A2026-01-1439046P51813Espacenet
JP 2026004568 A2026-01-1439047P51813Espacenet
JP 2026004568 A2026-01-1439048P51813Espacenet
JP 2025062604 A2025-04-149243P51813Espacenet
JP 2025062604 A2025-04-149244P51813Espacenet
JP 2025062604 A2025-04-149245P51813Espacenet
US 12006548 B22024-06-11336P51813Espacenet
US 11624747 B22023-04-1145P51813Espacenet
US 11446398 B22022-09-209243P51813Espacenet

1 to 10 of 83

See all 83 patents

Drugs2

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
RITLECITINIBCHEMBL4085457TEC family kinase inhibitorINHIBITORChEMBL
RITLECITINIB TOSYLATECHEMBL5314649TEC family kinase inhibitorINHIBITORChEMBL

Trials24

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07228390RITLECITINIBPHASE2ClinicalTrials.gov
NCT07226531RITLECITINIBClinicalTrials.gov
NCT07200128RITLECITINIBClinicalTrials.gov
NCT07152626RITLECITINIBPHASE2ClinicalTrials.gov
NCT07152119RITLECITINIB TOSYLATEClinicalTrials.gov
NCT07029828RITLECITINIBPHASE3ClinicalTrials.gov
NCT07029711RITLECITINIBPHASE3ClinicalTrials.gov
NCT06873945RITLECITINIBPHASE3ClinicalTrials.gov
NCT06573593RITLECITINIBClinicalTrials.gov
NCT06531109RITLECITINIBClinicalTrials.gov

1 to 10 of 24

See all 24 trials

NIH grants710

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleBMX papersNewest fiscal year
R01AI043957Structural Studies of a T cell Specific Tyrosine Kinase122025
P30CA016058Cancer Center Support Grant72025
P30CA008748Cancer Center Support Grant52025
P30CA016672Cancer Center Support Grant42025
P30CA021765Cancer Center Support Grant (CCSG)42025
P30CA093373Cancer Center Support Grant P3042025
P30CA006927Comprehensive Cancer Center Program at Fox Chase32025
P30CA076292Moffitt Cancer Center Support Grant32025
ZIAHL002346Tumor microenvironment in CLL and MCL: pathogenesis, targets, and therapy32025
K12CA133250OSU K12 Training Grant in Oncology22025

1 to 10 of 710Source NIH's project files

See all 710 nih grants

Papers981

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Long-read, whole-genome sequencing and chemotherapy response of two patient-derived organoids from a TP53- and KRAS-mutant ovarian carcinoma.bioRxiv202642465424PubTator, text miningPubMed
Riding toward Selectivity: Optimization of Covalent 7-Azaindole-Based BMX Kinase Inhibitors.J Med Chem202642441922PubTator, text miningPubMed
Discovery of Dihydropyrimido-Pyrimidine-Based Bone Marrow Tyrosine Kinase Gene in Chromosome X Protein Proteolysis-Targeting Chimeras for the Treatment of Prostate Cancer.ACS Med Chem Lett202642305213PubTator, text miningPubMed
Comorbidity risk characteristics of rheumatoid arthritis in the context of depression-associated lipid metabolism.Front Immunol202642273676PubTator, text miningPubMed
Systematic analysis of programmed cell death-related genes in sepsis reveals immune heterogeneity and enables patient stratification.Front Cell Dev Biol202642232056PubTator, text miningPubMed
Targeting the BMX in cancer: molecular mechanisms and emerging therapeutic strategies.J Enzyme Inhib Med Chem202642212521PubTator, text miningPubMed
Identification of BMX as a Potential Biomarker for Rheumatoid Arthritis Based on WGCNA, Machine Learning, and Experimental Validation.Immunol Invest202642204930PubTator, text miningPubMed
BMX inhibition overcomes small cell lung cancer chemoresistance by stabilizing E2F1 via ERK1/2-Cyclin D1/CDK4/6 axis.Signal Transduct Target Ther202641946708PubTator, text miningPubMed
Discovery of Covalent Ligands with AlphaFold3.J Am Chem Soc202641857796PubTator, text miningPubMed
Systems biology analysis uncovers a ROS-associated gene signature and immunomodulatory role of CLEC4E in ischemic stroke.PLoS One202641805714PubTator, text miningPubMed

1 to 10 of 981

See all 981 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/660

GET https://conductscience.org/api/genes/v1/660/patents?page=2