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Gene · 6613

SUMO2: small ubiquitin like modifier 2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. SUMO2: small ubiquitin like modifier 2. Genes, record 6613. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6613

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Gene

Symbol
SUMO2
HGNC
Name
small ubiquitin like modifier 2
HGNC
NCBI Gene ID
6613
NCBI Gene
HGNC ID
HGNC:11125
HGNC
Ensembl
ENSG00000188612
NCBI Gene
Aliases
HSMT3, SMT3B, SMT3H2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P61956Small ubiquitin-related modifier 29525Ensembl, GeneID, HGNC

Source UniProt

Patents51

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026108757 A2026-06-3033P61956Espacenet
EP 4650780 A22025-11-1913376P61956Espacenet
US 12351611 B22025-07-0833P61956Espacenet
JP 2025517970 A2025-06-1213376P61956Espacenet
JP 2025024198 A2025-02-1915969P61956Espacenet
US 12091437 B22024-09-1733P61956Espacenet
KR 1020240102916 A2024-07-03242P61956Espacenet
US 11976100 B22024-05-0739P61956Espacenet
US 11891420 B22024-02-0633P61956Espacenet
JP 2023523625 A2023-06-0639P61956Espacenet

1 to 10 of 51

See all 51 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,341

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleSUMO2 papersNewest fiscal year
P30CA008748Cancer Center Support Grant112025
P30CA033572Cancer Center Support Grant112025
T32CA009110Training in Areas Fundamental to Cancer Research112025
P30GM124165NE-CAT: A Resource for Advanced Macromolecular Crystallography92025
P30CA016672Cancer Center Support Grant52025
P30CA010815Consolidated Basic Cancer Research Program42025
R01AG011085Ubiquitin‐mediated proteolysis and cell cycle control42025
R01HD036071Genotype-Phenotype Relationships in Fragile X Families42025
P01CA092584Structural Cell Biology of DNA Repair Machines32025
P30CA014195Cancer Center Support Grant (CCSG)32025

1 to 10 of 1,341Source NIH's project files

See all 1,341 nih grants

Papers2,290

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Lumbrokinase ameliorates chronic social defeat stress-induced behavioral impairments through modulation of miR-340-5p and SUMO2 signaling.Neuropharmacology202642716376PubTator, text miningPubMed
PML-driven sumoylation of PML::RARA-bound repressors drives hematopoietic progenitor immortalization.J Exp Med202642663568PubTator, text miningPubMed
Ubiquitin-like proteins NEDD8 and SUMO2 control epithelial homeostasis, regeneration, and inflammation.Science202642348677PubTator, text miningPubMed
Direct Photoredox Synthesis of N-Linked Glycoproteins.J Am Chem Soc202642329120PubTator, text miningPubMed
TRIM28-mediated SUMOylation of SREBF1 drives PD‑L1 N‑glycosylation and immune evasion in bladder cancer.Cell Death Dis202642151123PubTator, text miningPubMed
Exon-skipping antisense oligonucleotides targeting SUMO1 and SUMO2 demonstrate chemosensitizing effects in NSCLC cells in tissue culture.Res Sq202642147169PubTator, text miningPubMed
Corrigendum to: "SUMO2-mediated SUMOylation of SH3GLB1 promotes ionizing radiation-induced hypertrophic cardiomyopathy through mitophagy activation'' [Europ. J. Pharmacol. 5 (2022) 174980 59897].Eur J Pharmacol202642115010PubTator, text miningPubMed
UBA2-High Osteosarcoma Suppresses Immune Infiltration by Autophagy-Mediated MHC-I Degradation.Cancer Immunol Res202642085301PubTator, text miningPubMed
RETRACTION: Downregulation of SUMO2 inhibits hepatocellular carcinoma cell proliferation, migration and invasion.FEBS Open Bio202641983998PubTator, text miningPubMed
Denaturing SUMO Immunoprecipitation From Mitotic Cells.Bio Protoc202641971162PubTator, text miningPubMed

1 to 10 of 2,290

See all 2,290 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/6613

GET https://conductscience.org/api/genes/v1/6613/patents?page=2