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Gene · 6614

SIGLEC1: sialic acid binding Ig like lectin 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. SIGLEC1: sialic acid binding Ig like lectin 1. Genes, record 6614. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6614

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Gene

Symbol
SIGLEC1
HGNC
Name
sialic acid binding Ig like lectin 1
HGNC
NCBI Gene ID
6614
NCBI Gene
HGNC ID
HGNC:11127
HGNC
Ensembl
ENSG00000088827
NCBI Gene
Aliases
CD169, FLJ00051, FLJ00055, FLJ00073, FLJ32150, SIGLEC-1, SN, dJ1009E24.1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9BZZ2Sialoadhesin1,7090Ensembl, GeneID, HGNC

Source UniProt

Patents53

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-196622Q9BZZ2Espacenet
EP 4640849 A22025-10-29952Q9BZZ2Espacenet
EP 4641201 A22025-10-296368Q9BZZ2Espacenet
JP 2025138725 A2025-09-252254Q9BZZ2Espacenet
JP 2025529142 A2025-09-043953Q9BZZ2Espacenet
US 12371689 B22025-07-293953Q9BZZ2Espacenet
JP 2025519096 A2025-06-24952Q9BZZ2Espacenet
JP 2025517969 A2025-06-126368Q9BZZ2Espacenet
JP 2025517970 A2025-06-126622Q9BZZ2Espacenet
WO 2025093745 A12025-05-08288Q9BZZ2Espacenet

1 to 10 of 53

See all 53 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,014

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleSIGLEC1 papersNewest fiscal year
P51OD011092Support for National Primate Research Center122025
P51OD011132Emory National Primate Research Center122025
P51OD011104Tulane National Primate Research Center92025
P30AI042853Providence/Boston Center for AIDS Research (CFAR)82025
UL1TR001863Yale Clinical and Translational Science Award82025
P30CA008748Cancer Center Support Grant72025
P30CA016359Cancer Center Support Grant72025
UL1TR001866Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational Success72025
P30CA016087Cancer Center Support Grant62025
P30CA013330Cancer Center Support Grant52025

1 to 10 of 2,014Source NIH's project files

See all 2,014 nih grants

Papers2,964

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Skin macrophage subsets in health and disease.J Dermatol Sci202642816244PubTator, text miningPubMed
Early monocyte subset signatures predict outcomes in unvaccinated COVID-19 patients.Front Immunol202642812399PubTator, text miningPubMed
Spatial Profiling and Prognostic Role of CD169+ Macrophages in Colorectal Cancer From Adjacent Nontumor Mucosa to Liver Metastasis.J Immunol Res202642811675PubTator, text miningPubMed
Mutations at Positions 181 and 185 Within the LCMV GP Protein Increase Tumor Cell Infectivity, Limit Induction of Type I Interferon, and Accelerate T Cell Activation.Viruses202642797832PubTator, text miningPubMed
Immune Profiling and Rapid Molecular Diagnostics in Severe Respiratory Infections and Sepsis: The Potential Clinical Perspective of CD169 and CD64.Microorganisms202642795651PubTator, text miningPubMed
Selective Whole-Blood Expression of Interferon-Stimulated Genes and TLR3/TLR7 in Type 1 Diabetes with Minimal Enterovirus-Targeted Amplification in Whole Blood.Genes (Basel)202642792959PubTator, text miningPubMed
A Novel Dominantly Segregating PSMB10 Splice-Site Variant in Familial Autoinflammatory Disease with Immunoproteasome and Interferon-Related Dysregulation.Genes (Basel)202642792891PubTator, text miningPubMed
CXCL2/CXCR2 pathway regulates CD169high large macrophages to promote progression of malignant pleural effusion from lung adenocarcinoma.Front Med (Lausanne)202642780770PubTator, text miningPubMed
Rethinking the Benign Nature of Class II Lupus Nephritis.bioRxiv202642779877PubTator, text miningPubMed
Single-cell profiling reveals context-dependent immune regulation shared by sepsis and systemic lupus erythematosus.Front Immunol202642755868PubTator, text miningPubMed

1 to 10 of 2,964

See all 2,964 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/6614

GET https://conductscience.org/api/genes/v1/6614/patents?page=2