ConductScience.org, home

Library / Genes

SNAP25: synaptosome associated protein 25

1 protein, 456 patents, 8 drugs, 724 trials, 3,687 NIH grants and 5,966 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolSNAP25HGNC
Namesynaptosome associated protein 25HGNC
NCBI Gene ID6616NCBI Gene
HGNC IDHGNC:11132HGNC
EnsemblENSG00000132639NCBI Gene
AliasesCMS18, DEE117, RIC-4, RIC4, SEC9, SNAP, SNAP-25, SUP, bA416N4.2, dJ1068F16.2NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P60880Synaptosomal-associated protein 2520614Ensembl, GeneID, HGNCUniProt

Patents 456

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1466067P60880Espacenet
EP 4641201 A22025-10-291140P60880Espacenet
JP 2025533447 A2025-10-074P60880Espacenet
WO 2025196445 A12025-09-254P60880Espacenet
EP 4588519 A22025-07-2310P60880Espacenet
EP 4588519 A22025-07-2311P60880Espacenet
EP 4588519 A22025-07-236P60880Espacenet
EP 4588519 A22025-07-237P60880Espacenet
EP 4588519 A22025-07-239P60880Espacenet
JP 2025517969 A2025-06-121140P60880Espacenet

Drugs 8

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
ABOBOTULINUMTOXINACHEMBL2108570Synaptosomal nerve-associated protein 25 (SNAP-25) inhibitorINHIBITORChEMBL
BOTULINUM TOXIN TYPE ACHEMBL4297862Synaptosomal nerve-associated protein 25 (SNAP-25) hydrolytic enzymeHYDROLYTIC ENZYMEChEMBL
DAXIBOTULINUMTOXINACHEMBL3707359Synaptosomal nerve-associated protein 25 (SNAP-25) inhibitorINHIBITORChEMBL
INCOBOTULINUMTOXINACHEMBL2108035Synaptosomal nerve-associated protein 25 (SNAP-25) inhibitorINHIBITORChEMBL
LETIBOTULINUMTOXINACHEMBL3707322Synaptosomal nerve-associated protein 25 (SNAP-25) hydrolytic enzymeHYDROLYTIC ENZYMEChEMBL
ONABOTULINUMTOXINACHEMBL1201574Synaptosomal nerve-associated protein 25 (SNAP-25) inhibitorINHIBITORChEMBL
PRABOTULINUMTOXIN ACHEMBL4297229Synaptosomal nerve-associated protein 25 (SNAP-25) proteolytic enzymePROTEOLYTIC ENZYMEChEMBL
TRENIBOTULINUMTOXINECHEMBL4594539Synaptosomal nerve-associated protein 25 (SNAP-25) hydrolytic enzymeHYDROLYTIC ENZYMEChEMBL

Trials 724

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07568314BOTULINUM TOXIN TYPE AClinicalTrials.gov
NCT07553065ONABOTULINUMTOXINAPHASE2ClinicalTrials.gov
NCT07553065INCOBOTULINUMTOXINAPHASE2ClinicalTrials.gov
NCT07553065BOTULINUM TOXIN TYPE APHASE2ClinicalTrials.gov
NCT07549113ONABOTULINUMTOXINAClinicalTrials.gov
NCT07549113LETIBOTULINUMTOXINAClinicalTrials.gov
NCT07549113BOTULINUM TOXIN TYPE AClinicalTrials.gov
NCT07545200ONABOTULINUMTOXINAClinicalTrials.gov
NCT07545200LETIBOTULINUMTOXINAClinicalTrials.gov
NCT07545200BOTULINUM TOXIN TYPE AClinicalTrials.gov

NIH grants 3687

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P01AG026276Antecedent Biomarkers for Alzheimer Disease: The Adult Children Study202,025NIH's project files
R01AI093504Novel therapeutic approaches to treatment of botulinum neurotoxin poisoning162,025NIH's project files
R01MH061876Synaptotagmin C2B Domain as a Ca2+ Sensing Module162,025NIH's project files
R01NS080833Biology and Engineering of Botulinum Neurotoxins.162,025NIH's project files
P30AG066444Alzheimer's Disease Research Center142,025NIH's project files
R01MH063105Molecular mechanisms of synaptic neurotransmitter release132,025NIH's project files
P30DK034854Integrated Epithelial and Muscosal Biology122,025NIH's project files
P30CA016042Cancer Center Support Grant112,025NIH's project files
U19AG032438Bridge Funding for Dominantly Inherited Alzheimer Network112,025NIH's project files
R28AA012725Brain Tissue Resource Center for Alcohol Research82,025NIH's project files

Papers 5966

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42800866PubTator, text miningPubMed
42784327PubTator, text miningPubMed
42770267PubTator, text miningPubMed
42655671PubTator, text miningPubMed
42649220PubTator, text miningPubMed
42646749PubTator, text miningPubMed
42633445PubTator, text miningPubMed
42624296PubTator, text miningPubMed
42621324PubTator, text miningPubMed
42582587PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license